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Actl7a Gene Detail
Summary
  • Symbol
    Actl7a
  • Name
    actin-like 7a
  • Synonyms
    Tact2, t-actin 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343051
    NCBI Gene: 11470
  • Gene Overview
    MyGene.info: ACTL7A
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:56743422-56744925 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 31.66 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    17
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343051
protein coding gene Chr4:56743413-56744925 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028309
protein coding gene Chr4:55503394-55504906 (+)
A/J MGP_AJ_G0028270
protein coding gene Chr4:53383202-53384714 (+)
AKR/J MGP_AKRJ_G0028219
protein coding gene Chr4:54855369-54856881 (+)
BALB/cJ MGP_BALBcJ_G0028289
protein coding gene Chr4:53539363-53540875 (+)
C3H/HeJ MGP_C3HHeJ_G0028010
protein coding gene Chr4:55365538-55367050 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028730
protein coding gene Chr4:57481920-57483432 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027448
protein coding gene Chr4:55069694-55071206 (+)
CBA/J MGP_CBAJ_G0027975
protein coding gene Chr4:59466380-59467892 (+)
DBA/2J MGP_DBA2J_G0028125
protein coding gene Chr4:53290794-53292306 (+)
FVB/NJ MGP_FVBNJ_G0028092
protein coding gene Chr4:52500751-52502263 (+)
LP/J MGP_LPJ_G0028224
protein coding gene Chr4:55604732-55606244 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028116
protein coding gene Chr4:62633455-62634967 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028766
protein coding gene Chr4:55035045-55036557 (+)
PWK/PhJ MGP_PWKPhJ_G0027173
protein coding gene Chr4:53270979-53272491 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027001
protein coding gene Chr4:54315391-54316903 (+)
WSB/EiJ MGP_WSBEiJ_G0027526
protein coding gene Chr4:54987134-54988646 (+)



Homology
more
  • Human Ortholog
    ACTL7A, actin like 7A
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ACTL7A, actin like 7A
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10881
    neXtProt AC: NX_Q9Y615
    UniProt: Q9Y615

  • Chr Location
    9q31.3; chr9:108862228-108863755 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11470 NCBI Gene Model | MGI Sequence Detail 1504 C57BL/6J ±  kb
transcript NM_009611 RefSeq | MGI Sequence Detail 1513 Not Specified  
polypeptide Q9QY84 UniProt | EBI | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Gene Ontology 5
  • Earliest
    J:56030 Chadwick BP, et al., Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31. Genomics. 1999 Jun 15;58(3):302-9
  • Latest
    J:175315 Boeda B, et al., Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A. J Biol Chem. 2011 Apr 1;286(13):11543-54

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory