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Rbmx Gene Detail
Summary
  • Symbol
    Rbmx
  • Name
    RNA binding motif protein, X chromosome
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343044
    NCBI Gene: 19655
  • Gene Overview
    MyGene.info: RBMX
Location & Maps
more
  • Sequence Map
    ChrX:57383530-57393036 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9507 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 31.64 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RBMX, RNA binding motif protein, X-linked
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RBMX, RNA binding motif protein, X-linked
    Orthology source: HomoloGene
  • Synonyms
    hnRNP-G, HNRNPG, HNRPG, MRXS11, RBMXP1, RBMXRT, RNMX
  • Links
    NCBI Gene ID: 27316
    neXtProt AC: NX_P38159

  • Chr Location
    Xq26.3; chrX:136869194-136880780 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human RBMX associations

Human Disease Mouse Models
       Mental Retardation, X-Linked, Syndromic 11; MRXS11   OMIM: 300238
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017821 VEGA Gene Model | MGI Sequence Detail 9507 C57BL/6J ±  kb
transcript OTTMUST00000043157 VEGA | MGI Sequence Detail 2019 Not Applicable  
polypeptide OTTMUSP00000019416 VEGA | MGI Sequence Detail 391 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    45 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000034845 RNA-binding motif protein, X chromosome
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR012604 RBM1CTR
    IPR000504 RNA recognition motif domain
    IPR003954 RNA recognition motif domain, eukaryote
Molecular
Reagents
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  • All nucleic 150
    cDNA 149
    Primer pair 1

    Microarray probesets 10
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:55846 Mazeyrat S, et al., RBMY evolved on the Y chromosome from a ubiquitously transcribed X-Y identical gene [letter]. Nat Genet. 1999 Jul;22(3):224-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory