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Ppef2 Gene Detail
Summary
  • Symbol
    Ppef2
  • Name
    protein phosphatase, EF hand calcium-binding domain 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1342304
    NCBI Gene: 19023
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:92226679-92256278 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 46.28 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1342304
protein coding gene Chr5:92226679-92256900 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029745
protein coding gene Chr5:93396061-93430428 (-)
A/J MGP_AJ_G0029711
protein coding gene Chr5:89691355-89721511 (-)
AKR/J MGP_AKRJ_G0029657
protein coding gene Chr5:92623772-92655723 (-)
BALB/cJ MGP_BALBcJ_G0029721
protein coding gene Chr5:90575024-90604696 (-)
C3H/HeJ MGP_C3HHeJ_G0029444
protein coding gene Chr5:93028643-93062463 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030175
protein coding gene Chr5:97103643-97145282 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027411
protein coding gene Chr5:85337466-85369942 (-)
CAST/EiJ MGP_CASTEiJ_G0028854
protein coding gene Chr5:92405193-92435127 (-)
CBA/J MGP_CBAJ_G0029414
protein coding gene Chr5:100462174-100509757 (-)
DBA/2J MGP_DBA2J_G0029558
protein coding gene Chr5:89735567-89768899 (-)
FVB/NJ MGP_FVBNJ_G0029517
protein coding gene Chr5:88583632-88613736 (-)
LP/J MGP_LPJ_G0029646
protein coding gene Chr5:93767824-93801528 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029546
protein coding gene Chr5:105391438-105424675 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030209
protein coding gene Chr5:92155619-92187608 (-)
PWK/PhJ MGP_PWKPhJ_G0028573
protein coding gene Chr5:88801405-88831719 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028408
protein coding gene Chr5:91522122-91551522 (-)
WSB/EiJ MGP_WSBEiJ_G0028933
protein coding gene Chr5:92614331-92645433 (-)



Homology
more
  • Human Ortholog
    PPEF2, protein phosphatase with EF-hand domain 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PPEF2, protein phosphatase with EF-hand domain 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PPP7CB
  • Links
    NCBI Gene ID: 5470
    neXtProt AC: NX_O14830
    UniProt: O14830

  • Chr Location
    4q21.1; chr4:75859872-75902528 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    11 phenotype references
Homozygotes for a targeted null mutation appear to be phenotypically normal.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029410 Ensembl Gene Model | MGI Sequence Detail 29600 C57BL/6J ±  kb
transcript ENSMUST00000201130 Ensembl | MGI Sequence Detail 2878 Not Applicable  
polypeptide ENSMUSP00000144157 Ensembl | MGI Sequence Detail 757 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory