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Uri1 Gene Detail
Summary
  • Symbol
    Uri1
  • Name
    URI1, prefoldin-like chaperone
  • Synonyms
    C80913, NNX3, Rmp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1342294
    NCBI Gene: 19777
  • Gene Overview
    MyGene.info: URI1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:37959992-38023551 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 25.29 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    490 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1342294
protein coding gene Chr7:37959992-38023575 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032099
protein coding gene Chr7:37489771-37556693 (-)
A/J MGP_AJ_G0032079
protein coding gene Chr7:36452717-36516332 (-)
AKR/J MGP_AKRJ_G0032012
protein coding gene Chr7:37357246-37423486 (-)
BALB/cJ MGP_BALBcJ_G0032086
protein coding gene Chr7:36761059-36828385 (-)
C3H/HeJ MGP_C3HHeJ_G0031803
protein coding gene Chr7:38244874-38309194 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032563
protein coding gene Chr7:39321837-39393425 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029596
protein coding gene Chr7:37165401-37226793 (-)
CAST/EiJ MGP_CASTEiJ_G0031138
protein coding gene Chr7:29496972-29566545 (-)
CBA/J MGP_CBAJ_G0031771
protein coding gene Chr7:40551524-40618047 (-)
DBA/2J MGP_DBA2J_G0031923
protein coding gene Chr7:36287081-36351733 (-)
FVB/NJ MGP_FVBNJ_G0031876
protein coding gene Chr7:36209389-36274154 (-)
LP/J MGP_LPJ_G0032000
protein coding gene Chr7:37847102-37910390 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031916
protein coding gene Chr7:39373208-39441323 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032578
protein coding gene Chr7:36962630-37032860 (-)
PWK/PhJ MGP_PWKPhJ_G0030860
protein coding gene Chr7:29670439-29735887 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030695
protein coding gene Chr7:26521453-26592683 (-)
WSB/EiJ MGP_WSBEiJ_G0031248
protein coding gene Chr7:37475899-37541088 (-)



Homology
more
  • Human Ortholog
    URI1, URI1, prefoldin like chaperone
  • Vertebrate Orthologs
    10
  • Human Ortholog
    URI1, URI1, prefoldin like chaperone
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C19orf2, NNX3, PPP1R19, RMP, URI
  • Links
    NCBI Gene ID: 8725
    neXtProt AC: NX_O94763
    UniProt: O94763

  • Chr Location
    19q12; chr19:29923644-30016612 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2813
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: URI1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030421 Ensembl Gene Model | MGI Sequence Detail 63560 C57BL/6J ±  kb
transcript ENSMUST00000206581 Ensembl | MGI Sequence Detail 1753 Not Applicable  
polypeptide ENSMUSP00000145738 Ensembl | MGI Sequence Detail 533 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    Genomic 3
    cDNA 19
    Primer pair 2

    Microarray probesets 9
Other
Accession IDs
less
MGI:2142349
References
more
  • Summaries
    All 44
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:52000 Van Leuven F, et al., Molecular cloning of a gene on chromosome 19q12 coding for a novel intracellular protein: analysis of expression in human and mouse tissues and in human tumor cells, particularly Reed-Sternberg cells in Hodgkin disease. Genomics. 1998 Dec 15;54(3):511-20
  • Latest
    J:254705 Tummala KS, et al., Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells. Cell Rep. 2017 Apr 18;19(3):584-600

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory