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Slc34a2
Gene Detail
Symbol

Name
ID
Slc34a2
solute carrier family 34 (sodium phosphate), member 2
MGI:1342284
Synonyms
D5Ertd227e, NaPi-2b, Npt2b, type IIb Na/Picotransporter
Feature Type
protein coding gene
Genetic Map
Chromosome 5
28.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:53038082-53071664 bp, + strand
From VEGA annotation of GRCm38

  33583 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2297  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC34A2
Gene Tree: Slc34a2

Human
homologs
SLC34A2, solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10568
neXtProt AC: NX_O95436

Human Synonyms: NAPI-3B, NAPI-IIb, NPTIIb

Human Chr (Location): 4p15.2; chr4:25655813-25678748 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human SLC34A2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Radiation induced(1) Targeted(5)
Genomic Mutations involving Slc34a2 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display embryonic lethality, embryonic growth arrest, failure of embryo turning and somitogenesis, impaired placental development and impaired yolk sac vascular remodeling.
 
Phenotype Images(4)
Interactions
Slc34a2 interacts with 297 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (23)    Tissues (23)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 23
cDNA source data(58)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc34a2 ; ZFIN slc34a2a, slc34a2b    NEW 
Molecular
reagents
All nucleic(59) cDNA(58) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026277 (Evidence)
Ensembl Gene Model ENSMUSG00000029188 (Evidence)
Entrez Gene 20531 (Evidence)
UniGene 284891
DFCI TC1574268
DoTS DT.94183469, DT.533864, DT.40162184
NIA Mouse Gene Index U005581
Consensus CDS Project CCDS19291.1
International Mouse Phenotyping Consortium Status Slc34a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026277 VEGA Gene Model | MGI Sequence Detail 33583 C57BL/6J ±  kb
transcript OTTMUST00000064978 VEGA | MGI Sequence Detail 4175 Not Applicable 
polypeptide OTTMUSP00000032326 VEGA | MGI Sequence Detail 697 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(88 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003841 Sodium-dependent phosphate transport protein
Protein Ontology PR:000015087 sodium-dependent phosphate transport protein 2B
References
(Earliest) J:51212 Hilfiker H, et al., Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14564-9
(Latest) J:211926 Ohata Y, et al., Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice. J Bone Miner Res. 2014 Jul;29(7):1627-38
All references(47)
Other
accession IDs
MGI:1098602, MGI:2140766

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory