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Gsto1
Gene Detail
 Symbol
Name
ID
Gsto1
glutathione S-transferase omega 1
MGI:1342273
Synonyms GSTX, p28
Feature Type protein coding gene
Genetic Map
Chromosome 19
40.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:47854970-47864790 bp, + strand
From VEGA annotation of GRCm38

  9821 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37971  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Gsto1

Human
homologs
Human Homolog GSTO1, glutathione S-transferase omega 1
NCBI Gene ID 9446
neXtProt AC  NX_P78417
Human Synonyms  GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R
Human Chr (Location)  10q25.1; chr10:104254194-104267464 (+)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a mutant allele do not display abnormal arsenate metabolism following acute arsenate exposure.
 
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cellular response to arsenic-containing substance, L-ascorbic acid biosynthetic process, ...
Component axon, basement membrane, ...
Function glutathione dehydrogenase (ascorbate) activity, glutathione transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (154)    Tissues (113)    Images (32)
Theiler Stages: 22, 23, 26, 28
Assay TypeResults
RNA in situ 148
Northern blot 6
cDNA source data(153)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(155) cDNA(153) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000028264 (Evidence)
Ensembl Gene ModelENSMUSG00000025068 (Evidence)
Entrez Gene14873 (Evidence)
UniGene378931
DFCITC1571996
DoTSDT.101403781, DT.110845756, DT.495718, DT.97411684
NIA Mouse Gene IndexU019552
EC1.20.4.2, 1.8.5.1, 2.5.1.18
Consensus CDS ProjectCCDS29893.1
International Mouse Knockout Project StatusGsto1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028264 VEGA Gene Model | MGI Sequence Detail 9821 C57BL/6J ±  kb
transcript OTTMUST00000070036 VEGA | MGI Sequence Detail 1182 Not Applicable 
polypeptide OTTMUSP00000035646 VEGA | MGI Sequence Detail 240 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(258 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004046 Glutathione S-transferase, C-terminal
InterPro IPR010987 Glutathione S-transferase, C-terminal-like
InterPro IPR004045 Glutathione S-transferase, N-terminal
InterPro IPR005442 Glutathione S-transferase, omega-class
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000008303 glutathione S-transferase omega-1
References (Earliest) J:53034 Kodym R, et al., The cloning and characterization of a new stress response protein. A mammalian member of a family of theta class glutathione s-transferase-like proteins. J Biol Chem. 1999 Feb 19;274(8):5131-7
(Latest) J:178114 Pei L, et al., Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome. Nat Med. 2011;17(11):1466-72
All references(42)
Other
accession IDs
MGI:2147425, MGI:2147485, MGI:2147644

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory