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Slc23a1
Gene Detail
Symbol

Name
ID
Slc23a1
solute carrier family 23 (nucleobase transporters), member 1
MGI:1341903
Synonyms
D18Ucla2, Slc23a2, SVCT1, YSPL3
Feature Type
protein coding gene
Genetic Map
Chromosome 18
19.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr18:35614604-35627244 bp, - strand
From VEGA annotation of GRCm38

  12641 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40769  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: xanthine/uracil permease
Gene Tree: Slc23a1

Human
homologs
Human Homolog SLC23A1, solute carrier family 23 (ascorbic acid transporter), member 1
NCBI Gene ID 9963
neXtProt AC  NX_Q9UHI7
Human Synonyms  SLC23A2, SVCT1, YSPL3
Human Chr (Location)  5q31.2; chr5:139367196-139384943 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit abnormal ascorbate homeostasis and early postnatal lethality associated with lethargy and lack of gastric milk. Heterozygous mice of homozgous dams exhibit a similar phenotype.
 
Interactions
Slc23a1 interacts with 258 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (195)    Tissues (195)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 195
cDNA source data(37)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(39) cDNA(37) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023952 (Evidence)
Ensembl Gene ModelENSMUSG00000024354 (Evidence)
Entrez Gene20522 (Evidence)
UniGene22702
DFCITC1582297, TC1687783
DoTSDT.101296541, DT.60117928, DT.94300116, DT.94379504
NIA Mouse Gene IndexU038321
Consensus CDS ProjectCCDS29144.1
International Mouse Knockout Project StatusSlc23a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023952 VEGA Gene Model | MGI Sequence Detail 12641 C57BL/6J ±  kb
transcript OTTMUST00000058542 VEGA | MGI Sequence Detail 3026 Not Applicable 
polypeptide OTTMUSP00000028374 VEGA | MGI Sequence Detail 605 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(6) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(53 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006043 Xanthine/uracil/vitamin C permease
Protein Ontology PR:000014996 solute carrier family 23 member 1
References
(Earliest) J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
(Latest) J:206636 Nualart F, et al., Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development. Histochem Cell Biol. 2013 Feb;139(2):233-47
All references(44)
Other
accession IDs
MGD-MRK-5036, MGI:91192

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory