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Ccr9 Gene Detail
Summary
  • Symbol
    Ccr9
  • Name
    chemokine (C-C motif) receptor 9
  • Synonyms
    Cmkbr10, GPR-9-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341902
    NCBI Gene: 12769
  • Gene Overview
    MyGene.info: CCR9
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr9:123678439-123781971 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      103533 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 74.33 cM, cytoband F
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
  • Vertebrate Orthologs
    12
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CC-CKR-9, CDw199, GPR28, GPR-9-6
  • Links
    NCBI Gene ID: 10803
    neXtProt AC: NX_P51686
    UniProt: P51686

  • Chr Location
    3p21.31; chr3:45886504-45903177 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 4 alleles in 4 genetic backgrounds
    4 phenotypes from multigenic genotypes
    34 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice have altered trafficing of lymphocytes to the intestine.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    110
  • Tissues
    61
  • cDNA Data
    23
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000036110 VEGA Gene Model | MGI Sequence Detail 103533 C57BL/6J ±  kb
    transcript OTTMUST00000092803 VEGA | MGI Sequence Detail 3004 Not Applicable  
    polypeptide OTTMUSP00000051359 VEGA | MGI Sequence Detail 369 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      1201 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 26
      Genomic 1
      cDNA 24
      Primer pair 1

      Microarray probesets 6
    References
    more
    • Summaries
      All 68
      Developmental Gene Expression 5
      Gene Ontology 5
      Phenotypes 34
    • Earliest
      J:54920 Zaballos A, et al., Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 1999 May 15;162(10):5671-5
    • Latest
      J:254765 Dzutsev A, et al., Differential T cell homing to colon vs. small intestine is imprinted by local CD11c(+) APCs that determine homing receptors. J Leukoc Biol. 2017 Dec;102(6):1381-1388
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/12/2018
    MGI 6.12     		The Jackson Laboratory