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Ccr9 Gene Detail
Summary
  • Symbol
    Ccr9
  • Name
    C-C motif chemokine receptor 9
  • Synonyms
    Cmkbr10, GPR-9-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341902
    NCBI Gene: 12769
  • Alliance
    genome feature page
  • Transcription Start Sites
    26 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:123596276-123612522 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 74.33 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    523 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341902
 protein coding gene Chr9:123507504-123613395 (+)
129S1/SvImJ ENSMUSG00200026409
 protein coding gene Chr9:120720245-120737452 (+)
A/J ENSMUSG00195025129
 protein coding gene Chr9:119870244-119887377 (+)
AKR/J ENSMUSG00220019305
 protein coding gene Chr9:120336640-120353763 (+)
BALB/cJ ENSMUSG00180024293
 protein coding gene Chr9:120410061-120427190 (+)
C3H/HeJ ENSMUSG00175016420
 protein coding gene Chr9:120646417-120663552 (+)
C57BL/6NJ ENSMUSG00215017834
 protein coding gene Chr9:120560197-120577320 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032863
 protein coding gene Chr9:119000975-119096214 (+)
CAST/EiJ ENSTCUG00005016730
 protein coding gene Chr9:120226146-120243883 (+)
CBA/J ENSMUSG00210036351
 protein coding gene Chr9:120364754-120381881 (+)
DBA/2J ENSMUSG00185016326
 protein coding gene Chr9:120700472-120717599 (+)
FVB/NJ ENSMUSG00205015769
 protein coding gene Chr9:120532009-120549148 (+)
JF1/MsJ ENSUMUG00000046314
 protein coding gene Chr9:120480061-120497258 (+)
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190013867
 protein coding gene Chr9:120307620-120324742 (+)
NZO/HlLtJ ENSMUSG00225023096
 protein coding gene Chr9:121125461-121142591 (+)
PWK/PhJ ENSLUMG00010035722
 protein coding gene Chr9:120375760-120392886 (+)
SPRET/EiJ ENSMSPG00010000482
 protein coding gene Chr9:122132800-122149109 (+)
WSB/EiJ ENSIUOG00005020851
 protein coding gene Chr9:119732152-119749310 (+)



Homology
more
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
  • Synonyms
    CC-CKR-9, CDw199, GPR28, GPR-9-6
  • Links
    NCBI Gene ID: 10803
    UniProt: P51686

  • Chr Location
    3p21.31; chr3:45884425-45904311 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 5 alleles in 5 genetic backgrounds
    4 phenotypes from multigenic genotypes
    57 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice have altered trafficing of lymphocytes to the intestine.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    61
  • cDNA Data
    24
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12769 NCBI Gene Model | MGI Sequence Detail 16247 C57BL/6J ±  kb
    transcript NM_001166625 RefSeq | MGI Sequence Detail 4392 ZRU/MplStud  
    polypeptide Q9WUT7 UniProt | EBI | MGI Sequence Detail 369 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 27
      Genomic 1
      cDNA 25
      Primer pair 1

      Microarray probesets 6
    References
    more
    • Summaries
      All 102
      Developmental Gene Expression 5
      Gene Ontology 10
      Phenotypes 57
    • Earliest
      J:54920 Zaballos A, et al., Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 1999 May 15;162(10):5671-5
    • Latest
      J:366040 Martinez-Rios J, et al., CCR9 shapes the immune microenvironment of colorectal cancer modulating the balance between intratumoral CD8+ T cell and FoxP3+ Helios+ Treg subpopulations. PLoS One. 2025;20(4):e0321930
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory