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Ccr9 Gene Detail
Summary
  • Symbol
    Ccr9
  • Name
    chemokine (C-C motif) receptor 9
  • Synonyms
    Cmkbr10, GPR-9-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341902
    NCBI Gene: 12769
  • Gene Overview
    MyGene.info: CCR9
  • Alliance
    gene page
  • Transcription Start Sites
    26 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:123596276-123612522 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 74.33 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    253 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341902
 protein coding gene Chr9:123507504-123613395 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035481
 protein coding gene Chr9:126735852-126835934 (+)
A/J MGP_AJ_G0035462
 protein coding gene Chr9:121887181-121989845 (+)
AKR/J MGP_AKRJ_G0035395
 protein coding gene Chr9:125155458-125255855 (+)
BALB/cJ MGP_BALBcJ_G0035458
 protein coding gene Chr9:121820421-121917925 (+)
C3H/HeJ MGP_C3HHeJ_G0035165
 protein coding gene Chr9:125600361-125701383 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035981
 protein coding gene Chr9:130236684-130341180 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032863
 protein coding gene Chr9:119000975-119096214 (+)
CAST/EiJ MGP_CASTEiJ_G0034470
 protein coding gene Chr9:125627583-125751588 (+)
CBA/J MGP_CBAJ_G0035133
 protein coding gene Chr9:134981857-135108158 (+)
DBA/2J MGP_DBA2J_G0035292
 protein coding gene Chr9:121332712-121431583 (+)
FVB/NJ MGP_FVBNJ_G0035239
 protein coding gene Chr9:120234418-120336906 (+)
LP/J MGP_LPJ_G0035371
 protein coding gene Chr9:127140106-127237579 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035280
 protein coding gene Chr9:135787852-135915772 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036000
 protein coding gene Chr9:125614442-125722088 (+)
PWK/PhJ MGP_PWKPhJ_G0034174
 protein coding gene Chr9:121782588-121889582 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034011
 protein coding gene Chr9:125727213-125826139 (+)
WSB/EiJ MGP_WSBEiJ_G0034590
 protein coding gene Chr9:125457262-125557570 (+)



Homology
more
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
  • Synonyms
    CC-CKR-9, CDw199, GPR28, GPR-9-6
  • Links
    NCBI Gene ID: 10803
    neXtProt AC: NX_P51686
    UniProt: P51686

  • Chr Location
    3p21.31; chr3:45886504-45903177 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 4 alleles in 4 genetic backgrounds
    4 phenotypes from multigenic genotypes
    42 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice have altered trafficing of lymphocytes to the intestine.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    61
  • cDNA Data
    24
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12769 NCBI Gene Model | MGI Sequence Detail 16247 C57BL/6J ±  kb
    transcript NM_001166625 RefSeq | MGI Sequence Detail 4392 C57BL/6  
    polypeptide Q9WUT7 UniProt | EBI | MGI Sequence Detail 369 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 27
      Genomic 1
      cDNA 25
      Primer pair 1

      Microarray probesets 6
    References
    more
    • Summaries
      All 79
      Developmental Gene Expression 5
      Gene Ontology 6
      Phenotypes 42
    • Earliest
      J:54920 Zaballos A, et al., Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 1999 May 15;162(10):5671-5
    • Latest
      J:313670 Huang Y, et al., Abrogation of CC Chemokine Receptor 9 Ameliorates Ventricular Electrical Remodeling in Mice After Myocardial Infarction. Front Cardiovasc Med. 2021;8:716219
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    01/12/2022
    MGI 6.17     		The Jackson Laboratory