Ccr9
Gene Detail

Symbol

Name
ID

Ccr9
chemokine (C-C motif) receptor 9
MGI:1341902

Synonyms

Cmkbr10, GPR-9-6

Feature Type

protein coding gene

Genetic Map

Chromosome 9
74.33 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr9:123678439-123781971 bp, + strand From VEGA annotation of GRCm38   103533 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:22546  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 3 zebrafish

Protein SuperFamily: chemokine receptor
Gene Tree: Ccr9

Human
homologs

Human Homolog		CCR9, chemokine (C-C motif) receptor 9
NCBI Gene ID		10803
neXtProt AC		NX_P51686
Human Synonyms		CC-CKR-9, CDw199, GPR28, GPR-9-6
Human Chr (Location)		3p21.3; chr3:45886504-45903175 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 

Homozygous null mice have altered trafficing of lymphocytes to the intestine.

 

Interactions

Ccr9 interacts with 360 markers (Mir7-1, Mir7-2, Mir7b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (16 annotations)

Process	chemokine-mediated signaling pathway, chemotaxis, ...
Component	cell surface, integral component of membrane, ...
Function	C-C chemokine receptor activity, chemokine receptor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)

Data Summary: Results (110)    Tissues (61)    Images (23)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	90
Northern blot	17
RT-PCR	3

cDNA source data(23)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(26) Genomic(1) cDNA(24) Primer pair(1)
Microarray probesets(6)

Other database
links

VEGA Gene Model	OTTMUSG00000036110 (Evidence)
Ensembl Gene Model	ENSMUSG00000029530 (Evidence)
Entrez Gene	12769 (Evidence)
UniGene	440604
DFCI	TC1582304
DoTS	DT.50316281, DT.101362018, DT.94225236
NIA Mouse Gene Index	U011200
Consensus CDS Project	CCDS23662.1
International Mouse Knockout Project Status	Ccr9

Sequences

Length	Strain/Species
genomic	OTTMUSG00000036110	VEGA Gene Model | MGI Sequence Detail	103533	C57BL/6J
transcript	OTTMUST00000092805	VEGA | MGI Sequence Detail	2830	Not Applicable
polypeptide	OTTMUSP00000051361	VEGA | MGI Sequence Detail	369	Not Applicable

All sequences(45) RefSeq(4) UniProt(2)

Polymorphisms

SNPs within 2kb(1202 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR004069	CC chemokine receptor 9
InterPro	IPR000355	Chemokine receptor family
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM
InterPro	IPR000276	G protein-coupled receptor, rhodopsin-like
Protein Ontology	PR:000001205	C-C chemokine receptor type 9

References

(Earliest) J:54920 Zaballos A, et al., Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 1999 May 15;162(10):5671-5
(Latest) J:214377 Zhang SL, et al., Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice. Blood. 2014 Jul 10;124(2):296-304
All references(67)