Ccr9 MGI Mouse Gene Detail - MGI:1341902 - chemokine (C-C motif) receptor 9

Ccr9 Gene Detail

Symbol

Ccr9
Name

chemokine (C-C motif) receptor 9
Synonyms

Cmkbr10, GPR-9-6

Feature Type

protein coding gene
IDs

MGI:1341902
NCBI Gene: 12769
Gene Overview

MyGene.info: CCR9

Sequence Map

Chr9:123678439-123781971 bp, + strand
From VEGA annotation of GRCm38

Mouse Genome Browser
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Sequence

103533 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 74.33 cM, cytoband F
Mapping Data

3 experiments

Human Ortholog

CCR9, C-C motif chemokine receptor 9

Vertebrate Orthologs

12

Human Ortholog

CCR9, C-C motif chemokine receptor 9
Orthology source: HomoloGene, HGNC
Synonyms

CC-CKR-9, CDw199, GPR28, GPR-9-6
Links

HGNC:1610

NCBI Gene ID: 10803

neXtProt AC: NX_P51686

UniProt: P51686
Chr Location

3p21.31; chr3:45886504-45903177 (+) GRCh38.p7

HomoloGene

Vertebrate Homology Class 22546
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;3 zebrafish;1 frog, western clawed;1 macaque, rhesus
HCOP

human homology predictions: CCR9
Protein SuperFamily

chemokine receptor
Gene Tree

Ccr9

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Phenotype Summary

16 phenotypes from 4 alleles in 4 genetic backgrounds
4 phenotypes from multigenic genotypes
33 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Targeted

4
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

11 strains or lines available

Homozygous null mice have altered trafficing of lymphocytes to the intestine.

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All GO Annotations

15
GO References

5

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

110
Tissues

61
cDNA Data

23
Literature Summary

5

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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Ccr9 interacts with 359 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

40
RefSeq

4
UniProt

2
CCDS

CCDS23662.1
UniGene

440604

			Length	Strain/Species	Flank
genomic	OTTMUSG00000036110	VEGA Gene Model \| MGI Sequence Detail	103533	C57BL/6J	± kb
transcript	OTTMUST00000092803	VEGA \| MGI Sequence Detail	3004	Not Applicable
polypeptide	OTTMUSP00000051359	VEGA \| MGI Sequence Detail	369	Not Applicable

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SNPs within 2kb

1201 from dbSNP Build 142

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UniProt

2 Sequences
Protein Ontology

PR:000001205 C-C chemokine receptor type 9

(term hierarchy)
InterPro Domains

IPR004069 CC chemokine receptor 9

IPR000355 Chemokine receptor family

IPR017452 GPCR, rhodopsin-like, 7TM

IPR000276 G protein-coupled receptor, rhodopsin-like

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All nucleic 26

Genomic 1

cDNA 24

Primer pair 1

Microarray probesets 6

Summaries

All 66

Developmental Gene Expression 5

Gene Ontology 5

Phenotypes 33
Earliest

J:54920 Zaballos A, et al., Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 1999 May 15;162(10):5671-5
Latest

J:238602 Evans-Marin HL, et al., Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development. PLoS One. 2015;10(7):e0134100

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 07/11/2017 MGI 6.10