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Ccr9 Gene Detail
Summary
  • Symbol
    Ccr9
  • Name
    chemokine (C-C motif) receptor 9
  • Synonyms
    Cmkbr10, GPR-9-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341902
    NCBI Gene: 12769
  • Gene Overview
    MyGene.info: CCR9
Location & Maps
more
  • Sequence Map
    Chr9:123678439-123781971 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      103533 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 74.33 cM, cytoband F
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
  • Vertebrate Orthologs
    12
  • Human Ortholog
    CCR9, C-C motif chemokine receptor 9
    Orthology source: HomoloGene
  • Synonyms
    CC-CKR-9, CDw199, GPR28, GPR-9-6
  • Links
    NCBI Gene ID: 10803
    neXtProt AC: NX_P51686

  • Chr Location
    3p21.3; chr3:45886504-45903177 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotypes from 4 alleles in 4 genetic backgrounds
    4 phenotypes from multigenic genotypes
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice have altered trafficing of lymphocytes to the intestine.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036110 VEGA Gene Model | MGI Sequence Detail 103533 C57BL/6J ±  kb
transcript OTTMUST00000092803 VEGA | MGI Sequence Detail 3004 Not Applicable  
polypeptide OTTMUSP00000051359 VEGA | MGI Sequence Detail 369 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1201 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000001205 C-C chemokine receptor type 9
  • InterPro Domains
    IPR004069 CC chemokine receptor 9
    IPR000355 Chemokine receptor family
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
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  • All nucleic 26
    Genomic 1
    cDNA 24
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 64
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 33
  • Earliest
    J:54920 Zaballos A, et al., Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 1999 May 15;162(10):5671-5
  • Latest
    J:219661 Wang X, et al., GPR18 is required for a normal CD8alphaalpha intestinal intraepithelial lymphocyte compartment. J Exp Med. 2014 Nov 17;211(12):2351-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory