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Msl3 Gene Detail
Summary
  • Symbol
    Msl3
  • Name
    MSL complex subunit 3
  • Synonyms
    Msl31, Msl3l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341851
    NCBI Gene: 17692
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:168654117-168673898 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 78.73 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341851
 protein coding gene ChrX:168651267-168674354 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036274
 protein coding gene ChrX:166856309-166877583 (-)
A/J MGP_AJ_G0036243
 protein coding gene ChrX:165991099-166012996 (-)
AKR/J MGP_AKRJ_G0036173
 protein coding gene ChrX:171294762-171319693 (-)
BALB/cJ MGP_BALBcJ_G0036238
 protein coding gene ChrX:163955470-163976791 (-)
C3H/HeJ MGP_C3HHeJ_G0035945
 protein coding gene ChrX:167166003-167188655 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036761
 protein coding gene ChrX:171696200-171718692 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033581
 protein coding gene ChrX:156712661-156736046 (-)
CAST/EiJ MGP_CASTEiJ_G0035232
 protein coding gene ChrX:146023557-146049411 (-)
CBA/J MGP_CBAJ_G0035919
 protein coding gene ChrX:176691087-176715428 (-)
DBA/2J MGP_DBA2J_G0036085
 protein coding gene ChrX:164756943-164778852 (-)
FVB/NJ MGP_FVBNJ_G0036017
 protein coding gene ChrX:163899553-163919012 (-)
LP/J MGP_LPJ_G0036170
 protein coding gene ChrX:167950362-167969287 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0036049
 protein coding gene ChrX:185413058-185436011 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036800
 protein coding gene ChrX:166315215-166341921 (-)
PWK/PhJ MGP_PWKPhJ_G0034931
 protein coding gene ChrX:142752996-142775428 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034750
 protein coding gene ChrX:146602605-146624633 (-)
WSB/EiJ MGP_WSBEiJ_G0035368
 protein coding gene ChrX:164124777-164148024 (-)



Homology
more
  • Human Ortholog
    MSL3, MSL complex subunit 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MSL3, MSL complex subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRSXBA, MRXS36, MRXSBA, MSL3L1
  • Links
    NCBI Gene ID: 10943
    neXtProt AC: NX_Q8N5Y2
    UniProt: Q8N5Y2

  • Chr Location
    Xp22.2; chrX:11758159-11775753 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with human MSL3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    674
  • Tissues
    25
  • cDNA Data
    17
  • Literature Summary
    5
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031358 Ensembl Gene Model | MGI Sequence Detail 19782 C57BL/6J ±  kb
transcript ENSMUST00000033725 Ensembl | MGI Sequence Detail 2399 Not Applicable  
polypeptide ENSMUSP00000033725 Ensembl | MGI Sequence Detail 525 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147958
References
more
  • Summaries
    All 31
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:56272 Prakash SK, et al., Characterization of a novel chromo domain gene in xp22.3 with homology to Drosophila msl-3. Genomics. 1999 Jul 1;59(1):77-84
  • Latest
    J:246912 Ye A, et al., PEG3 control on the mammalian MSL complex. PLoS One. 2017;12(6):e0178363
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/12/2021
MGI 6.16 		The Jackson Laboratory