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Msl3 Gene Detail
Summary
  • Symbol
    Msl3
  • Name
    male-specific lethal 3 homolog (Drosophila)
  • Synonyms
    Msl31, Msl3l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341851
    NCBI Gene: 17692
Location & Maps
more
  • Sequence Map
    ChrX:168654117-168673898 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      19782 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 78.73 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MSL3, male-specific lethal 3 homolog (Drosophila)
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MSL3, male-specific lethal 3 homolog (Drosophila)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MSL3L1
  • Links
    NCBI Gene ID: 10943
    neXtProt AC: NX_Q8N5Y2

  • Chr Location
    Xp22.3; chrX:11758159-11775753 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    3
  • Targeted
    3
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    31
  • Tissues
    22
  • cDNA Data
    16
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019558 VEGA Gene Model | MGI Sequence Detail 19782 C57BL/6J ±  kb
transcript OTTMUST00000046701 VEGA | MGI Sequence Detail 2399 Not Applicable  
polypeptide OTTMUSP00000021099 VEGA | MGI Sequence Detail 525 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    89 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147958
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:56272 Prakash SK, et al., Characterization of a novel chromo domain gene in xp22.3 with homology to Drosophila msl-3. Genomics. 1999 Jul 1;59(1):77-84
  • Latest
    J:206774 Wolstenholme JT, et al., Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes. Genes Brain Behav. 2013 Mar;12(2):166-80
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory