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Atrn
Gene Detail
Symbol

Name
ID
Atrn
attractin
MGI:1341628
Synonyms
Mgca, mKIAA0548
Feature Type
protein coding gene
Genetic Map
Chromosome 2
63.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(19)
Sequence Map
Chr2:130906495-131030333 bp, + strand
From VEGA annotation of GRCm38

  123839 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22542  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: ATRN
Gene Tree: Atrn

Human
homologs
ATRN, attractin
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 8455
neXtProt AC: NX_O75882

Human Synonyms: DPPT-L, MGCA

Human Chr (Location): 20p13; chr20:3471018-3651122 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(4) Spontaneous(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors.
 
Interactions
Atrn interacts with 442 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cerebellum development, inflammatory response, ...
Component cytoplasm, extracellular exosome, ...
Function carbohydrate binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (111)    Tissues (22)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 91
RT-PCR 20
cDNA source data(113)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase atrn    NEW 
Molecular
reagents
All nucleic(130) Genomic(15) cDNA(114) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000015539 (Evidence)
Ensembl Gene Model ENSMUSG00000027312 (Evidence)
Entrez Gene 11990 (Evidence)
UniGene 119936
DFCI TC1580004, TC1625686, TC1630486, TC1632483
DoTS DT.94138354, DT.101164697, DT.110664450, DT.91347809, DT.91399420, DT.490293, DT.91348821
NIA Mouse Gene Index U042374
Consensus CDS Project CCDS16751.1
International Mouse Phenotyping Consortium Status Atrn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015539 VEGA Gene Model | MGI Sequence Detail 123839 C57BL/6J ±  kb
transcript OTTMUST00000036906 VEGA | MGI Sequence Detail 8745 Not Applicable 
polypeptide OTTMUSP00000016559 VEGA | MGI Sequence Detail 1428 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(411 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
InterPro IPR000859 CUB domain
InterPro IPR013032 EGF-like, conserved site
InterPro IPR002049 EGF-like, laminin
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR011043 Galactose oxidase/kelch, beta-propeller
InterPro IPR006652 Kelch repeat type 1
InterPro IPR015915 Kelch-type beta propeller
InterPro IPR002165 Plexin
InterPro IPR016201 Plexin-like fold
Protein Ontology PR:000004501 attractin
References
(Earliest) J:24773 Lane PW, New mutants: Dancer, Athetoid, and mahogany. Mouse News Lett. 1958;19:25
(Latest) J:174243 Overton JD, et al., Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein. J Biol Chem. 2011 May 27;286(21):18914-29
All references(65)
Other
accession IDs
MGD-MRK-12216, MGI:2139403, MGI:96972

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory