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Dnm3 Gene Detail
Summary
  • Symbol
    Dnm3
  • Name
    dynamin 3
  • Synonyms
    9630020E24Rik, B230343F03Rik, mKIAA0820
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341299
    NCBI Gene: 103967
  • Gene Overview
    MyGene.info: DNM3
Location & Maps
more
  • Sequence Map
    Chr1:161982453-162478034 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      495582 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 69.95 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DNM3, dynamin 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNM3, dynamin 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Dyna III
  • Links
    NCBI Gene ID: 26052
    neXtProt AC: NX_Q9UQ16

  • Chr Location
    1q24.3; chr1:171841478-172418466 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotypes from multigenic genotypes
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Dnm3
  • Incidental Mutations
Mice homozygous for a targeted allele are viable and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029472 VEGA Gene Model | MGI Sequence Detail 495582 C57BL/6J ±  kb
transcript OTTMUST00000073176 VEGA | MGI Sequence Detail 7523 Not Applicable  
polypeptide OTTMUSP00000037853 VEGA | MGI Sequence Detail 863 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    3929 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
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  • All nucleic 14
    cDNA 12
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
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MGI:2138558, MGI:2444162
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:56117 Noakes PG, et al., Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation. J Comp Neurol. 1999 Aug 9;410(4):531-40
  • Latest
    J:222139 Meng J, et al., Molecular components required for resting and stimulated endocytosis of botulinum neurotoxins by glutamatergic and peptidergic neurons. FASEB J. 2013 Aug;27(8):3167-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory