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Dnm3 Gene Detail
Summary
  • Symbol
    Dnm3
  • Name
    dynamin 3
  • Synonyms
    9630020E24Rik, B230343F03Rik, mKIAA0820
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341299
    NCBI Gene: 103967
  • Gene Overview
    MyGene.info: DNM3
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:161982453-162478034 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 69.95 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3929 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341299
protein coding gene Chr1:161982450-162478328 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016658
protein coding gene Chr1:167289339-167806300 (-)
A/J MGP_AJ_G0016639
protein coding gene Chr1:160481817-160982499 (-)
AKR/J MGP_AKRJ_G0016605
protein coding gene Chr1:165358420-165863987 (-)
BALB/cJ MGP_BALBcJ_G0016600
protein coding gene Chr1:161030500-161510901 (-)
C3H/HeJ MGP_C3HHeJ_G0016424
protein coding gene Chr1:165575109-166072112 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017061
protein coding gene Chr1:172946417-173466590 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014770
protein coding gene Chr1:152573999-153040551 (-)
CAST/EiJ MGP_CASTEiJ_G0016004
protein coding gene Chr1:165199724-165720994 (-)
CBA/J MGP_CBAJ_G0016399
protein coding gene Chr1:179092702-179649921 (-)
DBA/2J MGP_DBA2J_G0016505
protein coding gene Chr1:159446137-159923828 (-)
FVB/NJ MGP_FVBNJ_G0016503
protein coding gene Chr1:157854969-158350104 (-)
LP/J MGP_LPJ_G0016576
protein coding gene Chr1:168403214-168925222 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016528
protein coding gene Chr1:186630228-187160812 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017097
protein coding gene Chr1:165201925-165693704 (-)
PWK/PhJ MGP_PWKPhJ_G0015790
protein coding gene Chr1:158623549-159100935 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015577
protein coding gene Chr1:164079239-164563952 (-)
WSB/EiJ MGP_WSBEiJ_G0016066
protein coding gene Chr1:165370673-165870346 (-)



Homology
more
  • Human Ortholog
    DNM3, dynamin 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNM3, dynamin 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Dyna III
  • Links
    NCBI Gene ID: 26052
    neXtProt AC: NX_Q9UQ16
    UniProt: Q9UQ16

  • Chr Location
    1q24.3; chr1:171841478-172418466 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotypes from multigenic genotypes
    10 phenotype references
Mice homozygous for a targeted allele are viable and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040265 Ensembl Gene Model | MGI Sequence Detail 495582 C57BL/6J ±  kb
transcript ENSMUST00000086074 Ensembl | MGI Sequence Detail 7523 Not Applicable  
polypeptide ENSMUSP00000083241 Ensembl | MGI Sequence Detail 863 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGI:2138558, MGI:2444162
References
more
  • Summaries
    All 44
    Developmental Gene Expression 5
    Gene Ontology 10
    Phenotypes 10
  • Earliest
    J:56117 Noakes PG, et al., Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation. J Comp Neurol. 1999 Aug 9;410(4):531-40
  • Latest
    J:256674 Gideons ES, et al., Chronic lithium treatment elicits its antimanic effects via BDNF-TrkB dependent synaptic downscaling. Elife. 2017 Jun 16;6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory