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Col14a1
Gene Detail
Symbol

Name
ID
Col14a1
collagen, type XIV, alpha 1
MGI:1341272
Synonyms
5730412L22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 15
21.96 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr15:55307750-55520803 bp, + strand
From VEGA annotation of GRCm38

  213054 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18741  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: COL14A1
Gene Tree: Col14a1

Human
homologs
COL14A1, collagen, type XIV, alpha 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 7373
neXtProt AC: NX_Q05707

Human Synonyms: UND

Human Chr (Location): 8q23; chr8:120125108-120373573 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation display abnormal tendon morphology and abnormal biomechanical properties of the skin and tendons.
 
Phenotype Images(2)
Interactions
Col14a1 interacts with 172 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell adhesion, collagen fibril organization, ...
Component collagen trimer, extracellular exosome, ...
Function poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (218)    Tissues (77)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 213
RT-PCR 3
cDNA source data(60)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA COL14A1 ; Xenbase col14a1 ; ZFIN col14a1a, col14a1b    NEW 
Molecular
reagents
All nucleic(62) cDNA(61) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000021422 (Evidence)
Ensembl Gene Model ENSMUSG00000022371 (Evidence)
Entrez Gene 12818 (Evidence)
UniGene 297859
DFCI TC1695196, TC1650109, TC1580464
DoTS DT.491094, DT.91326804, DT.87040531
NIA Mouse Gene Index U016255
Consensus CDS Project CCDS37076.1
International Mouse Phenotyping Consortium Status Col14a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021422 VEGA Gene Model | MGI Sequence Detail 213054 C57BL/6J ±  kb
transcript OTTMUST00000050766 VEGA | MGI Sequence Detail 6457 Not Applicable 
polypeptide OTTMUSP00000023788 VEGA | MGI Sequence Detail 1797 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(1414 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008160 Collagen triple helix repeat
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR001791 Laminin G domain
InterPro IPR002035 von Willebrand factor, type A
Protein Ontology PR:000005698 collagen alpha-1(XIV) chain
References
(Earliest) J:29901 Proetzel G, et al., Transforming growth factor-beta 3 is required for secondary palate fusion. Nat Genet. 1995 Dec;11(4):409-14
(Latest) J:189252 Tao G, et al., Collagen XIV is important for growth and structural integrity of the myocardium. J Mol Cell Cardiol. 2012 Nov;53(5):626-38
All references(40)
Other
accession IDs
MGI:1917736, MGI:2146190

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory