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Col14a1 Gene Detail
Summary
  • Symbol
    Col14a1
  • Name
    collagen, type XIV, alpha 1
  • Synonyms
    5730412L22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341272
    NCBI Gene: 12818
Location & Maps
more
  • Sequence Map
    Chr15:55307750-55520803 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      213054 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    COL14A1, collagen type XIV alpha 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    COL14A1, collagen type XIV alpha 1
    Orthology source: HomoloGene
  • Synonyms
    UND
  • Links
    NCBI Gene ID: 7373
    neXtProt AC: NX_Q05707

  • Chr Location
    8q23; chr8:120125108-120373573 (+)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    2 images
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    3
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Col14a1
  • Incidental Mutations
Mice homozygous for a null mutation display abnormal tendon morphology and abnormal biomechanical properties of the skin and tendons.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021422 VEGA Gene Model | MGI Sequence Detail 213054 C57BL/6J ±  kb
transcript OTTMUST00000050766 VEGA | MGI Sequence Detail 6457 Not Applicable  
polypeptide OTTMUSP00000023788 VEGA | MGI Sequence Detail 1797 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1414 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
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  • All nucleic 62
    cDNA 61
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
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MGI:1917736, MGI:2146190
References
more
  • Summaries
    All 39
    Developmental Gene Expression 11
    Diseases 1
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:29901 Proetzel G, et al., Transforming growth factor-beta 3 is required for secondary palate fusion. Nat Genet. 1995 Dec;11(4):409-14
  • Latest
    J:225061 Kouskoura T, et al., The etiology of cleft palate formation in BMP7-deficient mice. PLoS One. 2013;8(3):e59463

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory