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Aqp6 Gene Detail
Summary
  • Symbol
    Aqp6
  • Name
    aquaporin 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341204
    NCBI Gene: 11831
  • Gene Overview
    MyGene.info: AQP6
Location & Maps
more
  • Sequence Map
    Chr15:99601400-99605477 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4078 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.13 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    AQP6, aquaporin 6
  • Vertebrate Orthologs
    6
  • Human Ortholog
    AQP6, aquaporin 6
    Orthology source: HomoloGene
  • Synonyms
    AQP2L, KID
  • Links
    NCBI Gene ID: 363
    neXtProt AC: NX_Q13520

  • Chr Location
    12q13; chr12:49972837-49977139 (+)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    4
  • Genomic Mutations
    3 involving Aqp6
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043144 Ensembl Gene Model | MGI Sequence Detail 4078 C57BL/6J ±  kb
transcript ENSMUST00000023754 Ensembl | MGI Sequence Detail 2060 Not Applicable  
polypeptide ENSMUSP00000023754 Ensembl | MGI Sequence Detail 293 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    37 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 1
    cDNA 8
    Primer pair 3

    Microarray probesets 8
Other
Accession IDs
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MGI:2146063
References
more
  • Summaries
    All 42
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 6
    Phenotypes 24
  • Earliest
    J:52315 Knoers NV, et al., Aquaporin molecular biology and clinical abnormalities of the water transport channels. Curr Opin Pediatr. 1998 Aug;10(4):428-34
  • Latest
    J:217677 Snitow ME, et al., Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory