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Hmg20b
Gene Detail
Symbol

Name
ID
Hmg20b
high mobility group 20B
MGI:1341190
Synonyms
BRAF35, BRCA2-associated factor 35, Hmgx2, Hmgxb2, Smarce1r
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr10:81346048-81350480 bp, - strand
From VEGA annotation of GRCm38

  4433 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74949  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Hmg20b

Human
homologs
Human Homolog HMG20B, high mobility group 20B
NCBI Gene ID 10362
neXtProt AC  NX_Q9P0W2
Human Synonyms  BRAF25, BRAF35, HMGX2, HMGXB2, PP7706, pp8857, SMARCE1r, SOXL
Human Chr (Location)  19p13.3; chr19:3572945-3579083 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(16) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hmg20b interacts with 35 markers (Mir18, Mir18b, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cell cycle, chromatin modification, ...
Component BRCA2-BRAF35 complex, chromosome, ...
Function DNA binding, four-way junction DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (167)    Tissues (165)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 147
Northern blot 12
RT-PCR 8
cDNA source data(85)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(86) cDNA(85) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000017278 (Evidence)
Ensembl Gene ModelENSMUSG00000020232 (Evidence)
Entrez Gene15353 (Evidence)
UniGene38474
DFCITC1645024, TC1625631, TC1576183
DoTSDT.533003, DT.101735733, DT.94277044, DT.97367421, DT.97339330
PDB2CRJ
Consensus CDS ProjectCCDS24055.1
International Mouse Knockout Project StatusHmg20b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017278 VEGA Gene Model | MGI Sequence Detail 4433 C57BL/6J ±  kb
transcript OTTMUST00000041853 VEGA | MGI Sequence Detail 1621 Not Applicable 
polypeptide OTTMUSP00000018823 VEGA | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(98) RefSeq(12) UniProt(13)
Polymorphisms
SNPs within 2kb(8 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009071 High mobility group (HMG) box domain
Protein Ontology PR:000008627 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
References
(Earliest) J:55356 Wattler F, et al., Cloning, chromosomal location and expression analysis of murine Smarce1-related, a new member of the high-mobility 365 group gene family. Genomics. 1999 Sep 1;60(2):172-178
(Latest) J:184766 Ceballos-Chavez M, et al., Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8085-90
All references(47)
Other
accession IDs
MGI:2143872

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory