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Fhl3
Gene Detail
Symbol

Name
ID
Fhl3
four and a half LIM domains 3
MGI:1341092
Feature Type
protein coding gene
Genetic Map
Chromosome 4
57.88 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:124700701-124708611 bp, + strand
From VEGA annotation of GRCm38

  7911 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37928  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FHL3
Gene Tree: Fhl3

Human
homologs
FHL3, four and a half LIM domains 3
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2275
neXtProt AC: NX_Q13643

Human Synonyms: SLIM2

Human Chr (Location): 1p34; chr1:37996770-38005515 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Genomic Mutations involving Fhl3 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Fhl3 interacts with 123 markers (Mir1b, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process actin cytoskeleton organization
Component focal adhesion, nucleus, ...
Function actin binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (61)    Tissues (56)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 48
Northern blot 12
RT-PCR 1
cDNA source data(7)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase fhl3 ; ZFIN fhl3a    NEW 
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000009181 (Evidence)
Ensembl Gene Model ENSMUSG00000032643 (Evidence)
Entrez Gene 14201 (Evidence)
UniGene 331856
DFCI TC1589948
DoTS DT.55116393, DT.91333720
NIA Mouse Gene Index U004787
Consensus CDS Project CCDS38874.1
International Mouse Phenotyping Consortium Status Fhl3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009181 VEGA Gene Model | MGI Sequence Detail 7911 C57BL/6J ±  kb
transcript OTTMUST00000020762 VEGA | MGI Sequence Detail 1664 Not Applicable 
polypeptide OTTMUSP00000009522 VEGA | MGI Sequence Detail 289 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(70 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000031797 four and a half LIM domains protein 3
References
(Earliest) J:53041 Morgan MJ, et al., The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle. Biochem Biophys Res Commun. 1999 Feb 16;255(2):245-50
(Latest) J:168654 Chung YC, et al., Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory