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Fhl3 Gene Detail
Summary
  • Symbol
    Fhl3
  • Name
    four and a half LIM domains 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341092
    NCBI Gene: 14201
  • Gene Overview
    MyGene.info: FHL3
Location & Maps
more
  • Sequence Map
    Chr4:124700701-124708611 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7911 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 57.88 cM, cytoband D1
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    FHL3, four and a half LIM domains 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FHL3, four and a half LIM domains 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SLIM2
  • Links
    NCBI Gene ID: 2275
    neXtProt AC: NX_Q13643

  • Chr Location
    1p34; chr1:37996770-38005515 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 37928
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: FHL3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    2
  • Gene trapped
    8
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Fhl3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009181 VEGA Gene Model | MGI Sequence Detail 7911 C57BL/6J ±  kb
transcript OTTMUST00000020762 VEGA | MGI Sequence Detail 1664 Not Applicable  
polypeptide OTTMUSP00000009522 VEGA | MGI Sequence Detail 289 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    97 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031797 four and a half LIM domains protein 3
  • InterPro Domains
    IPR001781 Zinc finger, LIM-type
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:53041 Morgan MJ, et al., The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle. Biochem Biophys Res Commun. 1999 Feb 16;255(2):245-50
  • Latest
    J:168654 Chung YC, et al., Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory