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Ccni Gene Detail
Summary
  • Symbol
    Ccni
  • Name
    cyclin I
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341077
    NCBI Gene: 12453
  • Gene Overview
    MyGene.info: CCNI
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:93181933-93206495 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 47.29 cM, cytoband E3.3 - F1.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341077
protein coding gene Chr5:93181933-93206495 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029759
protein coding gene Chr5:94403341-94428823 (-)
A/J MGP_AJ_G0029725
protein coding gene Chr5:90653314-90677136 (-)
AKR/J MGP_AKRJ_G0029671
protein coding gene Chr5:93636425-93672539 (-)
BALB/cJ MGP_BALBcJ_G0029735
protein coding gene Chr5:91526351-91550793 (-)
C3H/HeJ MGP_C3HHeJ_G0029458
protein coding gene Chr5:94018928-94050554 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030189
protein coding gene Chr5:98143686-98170626 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027425
protein coding gene Chr5:86272636-86297111 (-)
CAST/EiJ MGP_CASTEiJ_G0028868
protein coding gene Chr5:93405898-93432910 (-)
CBA/J MGP_CBAJ_G0029428
protein coding gene Chr5:101559469-101588318 (-)
DBA/2J MGP_DBA2J_G0029572
protein coding gene Chr5:90698045-90720748 (-)
FVB/NJ MGP_FVBNJ_G0029531
protein coding gene Chr5:89556536-89580714 (-)
LP/J MGP_LPJ_G0029660
protein coding gene Chr5:94768606-94793197 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029560
protein coding gene Chr5:106437274-106469041 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030223
protein coding gene Chr5:93149559-93174130 (-)
PWK/PhJ MGP_PWKPhJ_G0028587
protein coding gene Chr5:89762928-89788831 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028422
protein coding gene Chr5:92486620-92511869 (-)
WSB/EiJ MGP_WSBEiJ_G0028947
protein coding gene Chr5:93618741-93642561 (-)



Homology
more
  • Human Ortholog
    CCNI, cyclin I
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCNI, cyclin I
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCNI1, CYC1, CYI
  • Links
    NCBI Gene ID: 10983
    neXtProt AC: NX_Q14094
    UniProt: Q14094

  • Chr Location
    4q21.1; chr4:77047155-77076013 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4979
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CCNI
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation are viable and fertile and do not display any gross physical or behavioral abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12453 NCBI Gene Model | MGI Sequence Detail 24563 C57BL/6J ±  kb
    transcript NM_017367 RefSeq | MGI Sequence Detail 2830 C57BL/6  
    polypeptide Q9Z2V9 UniProt | EBI | MGI Sequence Detail 377 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      Genomic 1
      cDNA 17
      Primer pair 1

      Microarray probesets 12
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:223852 Hagmann H, et al., Cyclin I and p35 determine the subcellular distribution of Cdk5. Am J Physiol Cell Physiol. 2015 Feb 15;308(4):C339-47

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory