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Sema4f Gene Detail
Summary
  • Symbol
    Sema4f
  • Name
    sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
  • Synonyms
    Sema W
  • Feature Type
    protein coding gene
  • IDs
    MGI:1340055
    NCBI Gene: 20355
  • Gene Overview
    MyGene.info: SEMA4F
Location & Maps
more
  • Sequence Map
    Chr6:82911885-82939769 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      27885 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 35.94 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SEMA4F, ssemaphorin 4F
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SEMA4F, ssemaphorin 4F
    Orthology source: HGNC, HomoloGene
  • Synonyms
    M-SEMA, m-Sema-M, PRO2353, S4F, SEMAM, SEMAW
  • Links
    NCBI Gene ID: 10505
    neXtProt AC: NX_O95754

  • Chr Location
    2p13.1; chr2:74654228-74694897 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Spontaneous
    1
  • Targeted
    5
  • Genomic Mutations
    1 involving Sema4f
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021185 VEGA Gene Model | MGI Sequence Detail 27885 C57BL/6J ±  kb
transcript OTTMUST00000050182 VEGA | MGI Sequence Detail 4086 Not Applicable  
polypeptide OTTMUSP00000023388 VEGA | MGI Sequence Detail 777 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    154 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    Genomic 1
    cDNA 22
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 11
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:53335 Encinas JA, et al., Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2491-6
  • Latest
    J:225235 Azzarelli R, et al., An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory