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Sema4f
Gene Detail
 Symbol
Name
ID
Sema4f
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
MGI:1340055
Synonyms Sema W
Feature Type protein coding gene
Genetic Map
Chromosome 6
35.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:82911885-82939769 bp, - strand
From VEGA annotation of GRCm38

  27885 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3147  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: semaphorin
Gene Tree: Sema4f

Human
homologs
Human Homolog SEMA4F, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
NCBI Gene ID 10505
neXtProt AC  NX_O95754
Human Synonyms  M-SEMA, m-Sema-M, PRO2353, S4F, SEMAM, SEMAW
Human Chr (Location)  2p13.1; chr2:74654228-74683854 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sema4f interacts with 282 markers (Mir10a, Mir10b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process axon guidance, cell differentiation, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function protein binding, receptor activity
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (58)    Tissues (49)    Images (10)
Theiler Stages: 19, 20, 22, 23, 24
Assay TypeResults
RNA in situ 58
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(1) cDNA(21) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000021185 (Evidence)
Ensembl Gene ModelENSMUSG00000000627 (Evidence)
Entrez Gene20355 (Evidence)
UniGene270543
DFCITC1582071, TC1592849, TC1604104
DoTSDT.55265015, DT.60101062, DT.91393551
NIA Mouse Gene IndexU027514
Consensus CDS ProjectCCDS20264.1, CCDS51816.1
International Mouse Knockout Project StatusSema4f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021185 VEGA Gene Model | MGI Sequence Detail 27885 C57BL/6J ±  kb
transcript OTTMUST00000050182 VEGA | MGI Sequence Detail 4086 Not Applicable 
polypeptide OTTMUSP00000023388 VEGA | MGI Sequence Detail 777 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(155 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002165 Plexin
InterPro IPR016201 Plexin-like fold
InterPro IPR015512 Seamphorin 4F
InterPro IPR027231 Semaphorin
InterPro IPR001627 Semaphorin/CD100 antigen
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000014625 semaphorin-4F
References (Earliest) J:53335 Encinas JA, et al., Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2491-6
(Latest) J:196818 Espana A, et al., Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus. Mol Cell Neurosci. 2012 May;50(1):93-102
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory