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Sema4f Gene Detail
Summary
  • Symbol
    Sema4f
  • Name
    sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
  • Synonyms
    Sema W
  • Feature Type
    protein coding gene
  • IDs
    MGI:1340055
    NCBI Gene: 20355
  • Gene Overview
    MyGene.info: SEMA4F
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:82911885-82939769 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 35.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    154 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1340055
protein coding gene Chr6:82911884-82939769 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030907
protein coding gene Chr6:83903320-83930771 (-)
A/J MGP_AJ_G0030876
protein coding gene Chr6:80700629-80728590 (-)
AKR/J MGP_AKRJ_G0030804
protein coding gene Chr6:83024738-83055865 (-)
BALB/cJ MGP_BALBcJ_G0030886
protein coding gene Chr6:80714420-80742478 (-)
C3H/HeJ MGP_C3HHeJ_G0030824
protein coding gene Chr6:101328142-101359748 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031346
protein coding gene Chr6:86182472-86212841 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028532
protein coding gene Chr6:79051848-79079199 (-)
CAST/EiJ MGP_CASTEiJ_G0029995
protein coding gene Chr6:83023175-83054365 (-)
CBA/J MGP_CBAJ_G0030573
protein coding gene Chr6:89598306-89627999 (-)
DBA/2J MGP_DBA2J_G0030726
protein coding gene Chr6:80019279-80047899 (-)
FVB/NJ MGP_FVBNJ_G0030679
protein coding gene Chr6:79227327-79255483 (-)
LP/J MGP_LPJ_G0030805
protein coding gene Chr6:83895279-83924454 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030715
protein coding gene Chr6:93901737-93931948 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031370
protein coding gene Chr6:82842114-82870311 (-)
PWK/PhJ MGP_PWKPhJ_G0029710
protein coding gene Chr6:78911659-78939523 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029538
protein coding gene Chr6:81686684-81713845 (-)
WSB/EiJ MGP_WSBEiJ_G0030076
protein coding gene Chr6:83279041-83307439 (-)



Homology
more
  • Human Ortholog
    SEMA4F, ssemaphorin 4F
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SEMA4F, ssemaphorin 4F
    Orthology source: HomoloGene, HGNC
  • Synonyms
    M-SEMA, m-Sema-M, PRO2353, S4F, SEMAM, SEMAW
  • Links
    NCBI Gene ID: 10505
    neXtProt AC: NX_O95754
    UniProt: O95754

  • Chr Location
    2p13.1; chr2:74654228-74699013 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000627 Ensembl Gene Model | MGI Sequence Detail 27885 C57BL/6J ±  kb
transcript ENSMUST00000000641 Ensembl | MGI Sequence Detail 4086 Not Applicable  
polypeptide ENSMUSP00000000641 Ensembl | MGI Sequence Detail 777 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    Genomic 1
    cDNA 24
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 43
    Developmental Gene Expression 13
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:53335 Encinas JA, et al., Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2491-6
  • Latest
    J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory