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Sema4f
Gene Detail
Symbol

Name
ID
Sema4f
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
MGI:1340055
Synonyms
Sema W
Feature Type
protein coding gene
Genetic Map
Chromosome 6
35.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:82911885-82939769 bp, - strand
From VEGA annotation of GRCm38

  27885 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3147  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: SEMA4F
Protein SuperFamily: semaphorin
Gene Tree: Sema4f

Human
homologs
SEMA4F, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10505
neXtProt AC: NX_O95754

Human Synonyms: M-SEMA, m-Sema-M, PRO2353, S4F, SEMAM, SEMAW

Human Chr (Location): 2p13.1; chr2:74654228-74694897 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Spontaneous(1) Targeted(5)
Genomic Mutations involving Sema4f (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sema4f interacts with 282 markers (Mir10a, Mir10b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process axon guidance, cell differentiation, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (58)    Tissues (49)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 58
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(1) cDNA(21) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000021185 (Evidence)
Ensembl Gene Model ENSMUSG00000000627 (Evidence)
Entrez Gene 20355 (Evidence)
UniGene 270543
DFCI TC1582071, TC1592849, TC1604104
DoTS DT.55265015, DT.60101062, DT.91393551
NIA Mouse Gene Index U027514
Consensus CDS Project CCDS20264.1, CCDS51816.1
International Mouse Phenotyping Consortium Status Sema4f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021185 VEGA Gene Model | MGI Sequence Detail 27885 C57BL/6J ±  kb
transcript OTTMUST00000050182 VEGA | MGI Sequence Detail 4086 Not Applicable 
polypeptide OTTMUSP00000023388 VEGA | MGI Sequence Detail 777 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(14) UniProt(3)
Polymorphisms
SNPs within 2kb(155 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016201 Plexin-like fold
InterPro IPR002165 Plexin repeat
InterPro IPR015512 Seamphorin 4F
InterPro IPR001627 Sema domain
InterPro IPR027231 Semaphorin
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000014625 semaphorin-4F
References
(Earliest) J:53335 Encinas JA, et al., Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2491-6
(Latest) J:196818 Espana A, et al., Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus. Mol Cell Neurosci. 2012 May;50(1):93-102
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory