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Cst9
Gene Detail
Symbol

Name
ID
Cst9
cystatin 9
MGI:1340053
Synonyms
cresp, M12, testatin
Feature Type
protein coding gene
Genetic Map
Chromosome 2
73.58 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:148835147-148838738 bp, + strand
From VEGA annotation of GRCm38

  3592 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49222  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog

HCOP human homology predictions: CST9, CST9L
Gene Tree: Cst9

Human
homologs
CST9, cystatin 9 (testatin)
Orthology source: HGNC

IDs:
NCBI Gene ID: 128822
neXtProt AC: NX_Q5W186

Human Synonyms: CLM, CTES7A

Human Chr (Location): 20p11.21; chr20:23602410-23605973 (-)  GRCh38.p2

  1 More Homolog(s):
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes are viable and fertile with normal testes development and morphology, sperm numbers and motility, and serum levels of testosterone, luteinizing hormone, and follicle-stimulating hormone.
 
Interactions
Cst9 interacts with 14 markers (Mir26a-1, Mir152, Mir155, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (15 records)
Data Summary: Results (88)    Tissues (38)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 4
RT-PCR 84
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(10) Primer pair(7)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000015723 (Evidence)
Ensembl Gene Model ENSMUSG00000027445 (Evidence)
Entrez Gene 13013 (Evidence)
UniGene 21005
DFCI TC1586146
DoTS DT.40164201
NIA Mouse Gene Index U002607
Consensus CDS Project CCDS16850.1
International Mouse Phenotyping Consortium Status Cst9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015723 VEGA Gene Model | MGI Sequence Detail 3592 C57BL/6J ±  kb
transcript OTTMUST00000037352 VEGA | MGI Sequence Detail 687 Not Applicable 
polypeptide OTTMUSP00000016735 VEGA | MGI Sequence Detail 137 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027214 Cystatin
InterPro IPR027213 Cystatin-9 like
InterPro IPR000010 Proteinase inhibitor I25, cystatin
Protein Ontology PR:000005971 cystatin-9
References
(Earliest) J:51224 Tohonen V, et al., Testatin: a cystatin-related gene expressed during early testis development. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14208-13
(Latest) J:220472 Zhao L, et al., Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1. Development. 2015 Mar 15;142(6):1083-8
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory