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Cst9 Gene Detail
Summary
  • Symbol
    Cst9
  • Name
    cystatin 9
  • Synonyms
    cresp, M12, testatin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1340053
    NCBI Gene: 13013
Location & Maps
more
  • Sequence Map
    Chr2:148835147-148838738 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3592 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 73.58 cM, cytoband H1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CST9, cystatin 9
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CST9, cystatin 9
    Orthology source: HGNC
  • Synonyms
    CLM, CTES7A
  • Links
    NCBI Gene ID: 128822
    neXtProt AC: NX_Q5W186

  • Chr Location
    20p11.21; chr20:23602410-23605973 (-)  GRCh38.p2

  • Human Ortholog
    CST9L, cystatin 9-like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA218C14.1, CTES7B
  • Links
    NCBI Gene ID: 128821
    neXtProt AC: NX_Q9H4G1

  • Chr Location
    20p11.21; chr20:23564732-23568749 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    11 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Cst9
  • Incidental Mutations
Homozygotes are viable and fertile with normal testes development and morphology, sperm numbers and motility, and serum levels of testosterone, luteinizing hormone, and follicle-stimulating hormone.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015723 VEGA Gene Model | MGI Sequence Detail 3592 C57BL/6J ±  kb
transcript OTTMUST00000037352 VEGA | MGI Sequence Detail 687 Not Applicable  
polypeptide OTTMUSP00000016735 VEGA | MGI Sequence Detail 137 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    78 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 17
    cDNA 10
    Primer pair 7

    Microarray probesets 4
References
more
  • Summaries
    All 40
    Developmental Gene Expression 15
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:51224 Tohonen V, et al., Testatin: a cystatin-related gene expressed during early testis development. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14208-13
  • Latest
    J:220472 Zhao L, et al., Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1. Development. 2015 Mar 15;142(6):1083-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory