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Cst9
Gene Detail
 Symbol
Name
ID
Cst9
cystatin 9
MGI:1340053
Synonyms cresp, M12, testatin
Feature Type protein coding gene
Genetic Map
Chromosome 2
73.58 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:148835147-148838738 bp, + strand
From VEGA annotation of GRCm38

  3592 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49222  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog

Gene Tree: Cst9

Human
homologs
Human Homolog CST9L, cystatin 9-like
NCBI Gene ID 128821
neXtProt AC  NX_Q9H4G1
Human Synonyms  bA218C14.1, CTES7B
Human Chr (Location)  20p11.21; chr20:23564732-23568749 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes are viable and fertile with normal testes development and morphology, sperm numbers and motility, and serum levels of testosterone, luteinizing hormone, and follicle-stimulating hormone.
 
Interactions
Cst9 interacts with 15 markers (Mir26a-1, Mir152, Mir155, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process negative regulation of peptidase activity
Component extracellular region
Function cysteine-type endopeptidase inhibitor activity, peptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (72)    Tissues (24)    Images (1)
Theiler Stages: 18, 20, 21, 22, 24, 28
Assay TypeResults
RT-PCR 72
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(9) Primer pair(5)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000015723 (Evidence)
Ensembl Gene ModelENSMUSG00000027445 (Evidence)
Entrez Gene13013 (Evidence)
UniGene21005
DFCITC1586146
DoTSDT.40164201
NIA Mouse Gene IndexU002607
Consensus CDS ProjectCCDS16850.1
International Mouse Knockout Project StatusCst9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015723 VEGA Gene Model | MGI Sequence Detail 3592 C57BL/6J ±  kb
transcript OTTMUST00000037352 VEGA | MGI Sequence Detail 687 Not Applicable 
polypeptide OTTMUSP00000016735 VEGA | MGI Sequence Detail 137 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027214 Cystatin
InterPro IPR027213 Cystatin-9 like
InterPro IPR000010 Proteinase inhibitor I25, cystatin
Protein Ontology PR:000005971 cystatin-9
References (Earliest) J:51224 Tohonen V, et al., Testatin: a cystatin-related gene expressed during early testis development. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14208-13
(Latest) J:192497 Georg I, et al., Sox9 and Sox8 are required for basal lamina integrity of testis cords and for suppression of FOXL2 during embryonic testis development in mice. Biol Reprod. 2012 Oct;87(4):99
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory