Nfkbil1
Gene Detail

Symbol Name ID

Nfkbil1 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1 MGI:1340031

Synonyms

Def-7

Feature Type

protein coding gene

Genetic Map

Chromosome 17

18.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr17:35220175-35235792 bp, - strand From VEGA annotation of GRCm38   15618 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3671  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Nfkbil1

Human homologs

Human Homolog		NFKBIL1, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NCBI Gene ID		4795
neXtProt AC		NX_Q9UBC1
Human Synonyms		IKBL, LST1, NFKBIL
Human Chr (Location)		6p21.3; chr6:31514628-31526606 (+)  GRCh37.p13
Disease Associations		(1) Diseases Associated with Human NFKBIL1

Alleles and phenotypes

All alleles(10) : Targeted(2) Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	cellular response to lipopolysaccharide, I-kappaB kinase/NF-kappaB signaling, ...
Component	cytosol, intermediate filament cytoskeleton, ...
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (7)    Tissues (7)    Images (1)
Theiler Stages: 15, 17, 19, 23

Assay Type	Results
RNA in situ	7

cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(23) Genomic(6) cDNA(16) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000031450 (Evidence)
Ensembl Gene Model	ENSMUSG00000042419 (Evidence)
Entrez Gene	18038 (Evidence)
UniGene	300795
DFCI	TC1584022
DoTS	DT.50315693
NIA Mouse Gene Index	U037746
Consensus CDS Project	CCDS28693.1
International Mouse Knockout Project Status	Nfkbil1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031450	VEGA Gene Model | MGI Sequence Detail	15618	C57BL/6J
transcript	OTTMUST00000077934	VEGA | MGI Sequence Detail	1447	Not Applicable
polypeptide	OTTMUSP00000041325	VEGA | MGI Sequence Detail	381	Not Applicable

All sequences(29) RefSeq(10) UniProt(2)

Polymorphisms

SNPs within 2kb(285 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR002110	Ankyrin repeat
InterPro	IPR020683	Ankyrin repeat-containing domain
Protein Ontology	PR:000011180	NF-kappa-B inhibitor-like protein 1

References

(Earliest) J:53338 Handel-Fernandez ME, et al., Sequence analysis and expression of a mouse homolog of human IkappaBL gene. Biochim Biophys Acta. 1999 Feb 16;1444(2):306-10
(Latest) J:180263 Chiba T, et al., IkappaBL, a novel member of the nuclear IkappaB family, inhibits inflammatory cytokine expression. FEBS Lett. 2011 Nov 16;585(22):3577-81
All references(32)