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Nfkbil1
Gene Detail
Symbol

Name
ID
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
MGI:1340031
Synonyms
Def-7
Feature Type
protein coding gene
Genetic Map
Chromosome 17
18.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:35220175-35235792 bp, - strand
From VEGA annotation of GRCm38

  15618 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3671  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Nfkbil1

Human
homologs
Human Homolog NFKBIL1, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NCBI Gene ID 4795
neXtProt AC  NX_Q9UBC1
Human Synonyms  IKBL, LST1, NFKBIL
Human Chr (Location)  6p21.3; chr6:31546851-31558829 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human NFKBIL1
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Genomic Mutations involving Nfkbil1 (1)
Interactions
Nfkbil1 interacts with 31 markers (Mir26a-1, Mir34a, Mir140, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cellular response to lipopolysaccharide, I-kappaB kinase/NF-kappaB signaling, ...
Component cytosol, intermediate filament cytoskeleton, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (7)    Tissues (7)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 7
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(6) cDNA(16) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000031450 (Evidence)
Ensembl Gene ModelENSMUSG00000042419 (Evidence)
Entrez Gene18038 (Evidence)
UniGene300795
DFCITC1584022
DoTSDT.50315693
NIA Mouse Gene IndexU037746
Consensus CDS ProjectCCDS28693.1
International Mouse Knockout Project StatusNfkbil1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031450 VEGA Gene Model | MGI Sequence Detail 15618 C57BL/6J ±  kb
transcript OTTMUST00000077934 VEGA | MGI Sequence Detail 1447 Not Applicable 
polypeptide OTTMUSP00000041325 VEGA | MGI Sequence Detail 381 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(10) UniProt(3)
Polymorphisms
SNPs within 2kb(285 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
Protein Ontology PR:000011180 NF-kappa-B inhibitor-like protein 1
References
(Earliest) J:53338 Handel-Fernandez ME, et al., Sequence analysis and expression of a mouse homolog of human IkappaBL gene. Biochim Biophys Acta. 1999 Feb 16;1444(2):306-10
(Latest) J:180263 Chiba T, et al., IkappaBL, a novel member of the nuclear IkappaB family, inhibits inflammatory cytokine expression. FEBS Lett. 2011 Nov 16;585(22):3577-81
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory