About   Help   FAQ
Mettl1 Gene Detail
Summary
  • Symbol
    Mettl1
  • Name
    methyltransferase like 1
  • Synonyms
    2810012D02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339986
    NCBI Gene: 17299
  • Gene Overview
    MyGene.info: METTL1
Location & Maps
more
  • Sequence Map
    Chr10:127041414-127046365 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4952 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 74.50 cM, cytoband D3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    METTL1, methyltransferase like 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    METTL1, methyltransferase like 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C12orf1, TRM8, TRMT8, YDL201w
  • Links
    NCBI Gene ID: 4234
    neXtProt AC: NX_Q9UBP6

  • Chr Location
    12q13; chr12:57768471-57772131 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030570 VEGA Gene Model | MGI Sequence Detail 4952 C57BL/6J ±  kb
transcript OTTMUST00000075701 VEGA | MGI Sequence Detail 1791 Not Applicable  
polypeptide OTTMUSP00000039739 VEGA | MGI Sequence Detail 268 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    44 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010341 tRNA (guanine-N(7)-)-methyltransferase
  • EC
  • InterPro Domains
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
    IPR025763 tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote
    IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type
Molecular
Reagents
less
  • All nucleic 39
    cDNA 39

    Microarray probesets 5
Other
Accession IDs
less
MGI:1917465
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:55326 Bahr A, et al., Molecular analysis of METTL1, a novel human methyltransferase-like gene with a high degree of phylogenetic conservation. Genomics. 1999 May 1;57(3):424-8
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory