About   Help   FAQ
Myh13 Gene Detail
Summary
  • Symbol
    Myh13
  • Name
    myosin, heavy polypeptide 13, skeletal muscle
  • Synonyms
    EO Myosin, extraocular myosin, MyHC-eo
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339967
    NCBI Gene: 544791
  • Gene Overview
    MyGene.info: MYH13
Location & Maps
more
  • Sequence Map
    Chr11:67321658-67371586 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      49929 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 40.85 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MYH13, myosin heavy chain 13
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MYH13, myosin heavy chain 13
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MyHC-eo, MyHC-IIL
  • Links
    NCBI Gene ID: 8735
    neXtProt AC: NX_Q9UKX3

  • Chr Location
    17p13; chr17:10300866-10373005 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Targeted
    2
  • Genomic Mutations
    1 involving Myh13
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005927 VEGA Gene Model | MGI Sequence Detail 49929 C57BL/6J ±  kb
transcript OTTMUST00000013195 VEGA | MGI Sequence Detail 6062 Not Applicable  
polypeptide OTTMUSP00000006123 VEGA | MGI Sequence Detail 1938 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    515 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR000048 IQ motif, EF-hand binding site
    IPR001609 Myosin head, motor domain
    IPR027401 Myosin-like IQ motif-containing domain
    IPR004009 Myosin, N-terminal, SH3-like
    IPR002928 Myosin tail
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 8
    Genomic 6
    cDNA 1
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:53871 Winters LM, et al., The human extraocular muscle myosin heavy chain gene (MYH13) maps to the cluster of fast and developmental myosin genes on chromosome 17. Genomics. 1998 Nov 15;54(1):188-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory