About   Help   FAQ
Ftcd
Gene Detail
 Symbol
Name
ID
Ftcd
formiminotransferase cyclodeaminase
MGI:1339962
Synonyms glutamate formiminotransferase
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr10:76575648-76590338 bp, + strand
From VEGA annotation of GRCm38

  14691 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4848  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ftcd

Human
homologs
Human Homolog FTCD, formimidoyltransferase cyclodeaminase
NCBI Gene ID 10841
neXtProt AC  NX_O95954
Human Synonyms  LCHC1
Human Chr (Location)  21q22.3; chr21:46136151-46155592 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human FTCD
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process cellular metabolic process, cytoskeleton organization, ...
Component cytoplasm, cytoskeleton, ...
Function catalytic activity, folic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (164)    Tissues (133)    Images (10)
Theiler Stages: 13, 15, 17, 20, 22, 23, 26, 28
Assay TypeResults
RNA in situ 142
RT-PCR 22
cDNA source data(40)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(44) Genomic(1) cDNA(40) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020446 (Evidence)
Ensembl Gene ModelENSMUSG00000001155 (Evidence)
Entrez Gene14317 (Evidence)
UniGene36278
DFCITC1582322
DoTSDT.101399969, DT.488456, DT.97362306
NIA Mouse Gene IndexU011681
EC2.1.2.5, 4.3.1.4
Consensus CDS ProjectCCDS23950.1
International Mouse Knockout Project StatusFtcd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020446 VEGA Gene Model | MGI Sequence Detail 14691 C57BL/6J ±  kb
transcript OTTMUST00000048531 VEGA | MGI Sequence Detail 1933 Not Applicable 
polypeptide OTTMUSP00000022267 VEGA | MGI Sequence Detail 541 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(43 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007044 Cyclodeaminase/cyclohydrolase
InterPro IPR004227 Formiminotransferase catalytic domain
InterPro IPR013802 Formiminotransferase, C-terminal subdomain
InterPro IPR012886 Formiminotransferase, N-terminal subdomain
InterPro IPR022384 Formiminotransferas, N- and C-terminal subdomains
Protein Ontology PR:000007689 formimidoyltransferase-cyclodeaminase
References (Earliest) J:61527 Solans A, et al., Cloning and characterization of human FTCD on 21q22.3, a candidate gene for glutamate formiminotransferase deficiency. Cytogenet Cell Genet. 2000;88(1-2):43-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory