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S100a10
Gene Detail
Symbol

Name
ID
S100a10
S100 calcium binding protein A10 (calpactin)
MGI:1339468
Synonyms
42C, CAL12, Cal1l, CLP11, p10
Feature Type
protein coding gene
Genetic Map
Chromosome 3
40.51 cM, cytoband F1-F2
Detailed Genetic Map ± 1 cM


Mapping data(11)
Sequence Map
Chr3:93555080-93564643 bp, + strand
From VEGA annotation of GRCm38

  9564 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2228  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: S-100 protein
Gene Tree: S100a10

Human
homologs
Human Homolog S100A10, S100 calcium binding protein A10
NCBI Gene ID 6281
neXtProt AC  NX_P60903
Human Synonyms  42C, ANX2L, ANX2LG, Ca[1], CAL1L, CLP11, GP11, p10, P11
Human Chr (Location)  1q21; chr1:151982910-151994238 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(41) : Gene trapped(36) Targeted(5)
 
Mice homozygous for a knock-out allele display a depression-like phenotype, decreased responsiveness to 5-HT1B receptor agonists, and reduced behavioral reactions to an antidepressant.
 
Interactions
S100a10 interacts with 40 markers (Mir10b, Mir30b, Mir103-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (11 records)
Data Summary: Results (607)    Tissues (211)    Images (88)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 605
RT-PCR 2
cDNA source data(147)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(152) cDNA(148) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022124 (Evidence)
Ensembl Gene ModelENSMUSG00000041959 (Evidence)
Entrez Gene20194 (Evidence)
UniGene1
DFCITC1610278, TC1574176
DoTSDT.55282592, DT.111050644, DT.536535
NIA Mouse Gene IndexU003534
Consensus CDS ProjectCCDS38526.1
International Mouse Knockout Project StatusS100a10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022124 VEGA Gene Model | MGI Sequence Detail 9564 C57BL/6J ±  kb
transcript OTTMUST00000052509 VEGA | MGI Sequence Detail 685 Not Applicable 
polypeptide OTTMUSP00000024909 VEGA | MGI Sequence Detail 97 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(4) UniProt(5)
Polymorphisms
RFLP(2) : SNPs within 2kb(134 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
InterPro IPR001751 S100/Calbindin-D9k, conserved site
Protein Ontology PR:000014403 protein S100-A10
References
(Earliest) J:8809 Saris CJ, et al., cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I). J Biol Chem. 1987 Aug 5;262(22):10663-71
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(67)
Other
accession IDs
MGD-MRK-1728, MGI:2139574, MGI:2139857, MGI:88247

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory