S100a6
Gene Detail

Symbol Name ID

S100a6 S100 calcium binding protein A6 (calcyclin) MGI:1339467

STS

D3Nds7

Synonyms

2A9, 5B10, Cacy, CALCYCLIN, PRA

Feature Type

protein coding gene

Genetic Map

Chromosome 3

39.35 cM, cytoband F1-F2
Detailed Genetic Map ± 1 cM


Mapping data(18)

Sequence Map

Chr3:90612894-90614414 bp, + strand From NCBI annotation of GRCm38   1521 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7925  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: S-100 protein
Gene Tree: S100a6

Human homologs

Human Homolog		S100A6, S100 calcium binding protein A6
NCBI Gene ID		6277
neXtProt AC		NX_P06703
Human Synonyms		2A9, 5B10, CABP, CACY, PRA
Human Chr (Location)		1q21; chr1:153507076-153508717 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (21 annotations)

Process	ion transmembrane transport
Component	cytoplasm, cytosol, ...
Function	calcium-dependent protein binding, calcium ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (11 records)
Data Summary: Results (12)    Tissues (10)    Images (3)
Theiler Stages: 21, 22, 24, 26, 28

Assay Type	Results
Immunohistochemistry	4
RNA in situ	8

cDNA source data(164)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(170) Genomic(3) cDNA(167)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000001025 (Evidence)
Entrez Gene	20200 (Evidence)
UniGene	100144
DFCI	TC1573037, TC1595642, TC1610338
DoTS	DT.101147680, DT.537157, DT.94218156, DT.94340667, DT.97405040
Consensus CDS Project	CCDS38506.1
International Mouse Knockout Project Status	S100a6

Sequences

Length	Strain/Species
genomic	20200	NCBI Gene Model | MGI Sequence Detail	1521	C57BL/6J
transcript	NM_011313	RefSeq | MGI Sequence Detail	719	C57BL/6
polypeptide	P14069	UniProt | EBI | MGI Sequence Detail	89	Not Applicable

All sequences(32) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(2) : SNPs(37 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR018247	EF-Hand 1, calcium-binding site
InterPro	IPR002048	EF-hand domain
InterPro	IPR011992	EF-hand-like domain
InterPro	IPR013787	S100/CaBP-9k-type, calcium binding, subdomain
InterPro	IPR001751	S100/Calbindin-D9k, conserved site
Protein Ontology	PR:000014413	protein S100-A6

Graphical View of Protein Domain Structure

References

(Earliest) J:15754 Edwards DR, et al., Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements. Mol Cell Biol. 1985 Nov;5(11):3280-8
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(71)

Other accession IDs

MGD-MRK-1721, MGI:88241