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S100a6 Gene Detail
Summary
  • Symbol
    S100a6
  • Name
    S100 calcium binding protein A6 (calcyclin)
  • Synonyms
    2A9, 5B10, Cacy, CALCYCLIN, PRA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339467
    NCBI Gene: 20200
Location & Maps
more
  • Sequence Map
    Chr3:90612882-90624181 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11300 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    S100A6, S100 calcium binding protein A6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    S100A6, S100 calcium binding protein A6
    Orthology source: HomoloGene
  • Synonyms
    2A9, 5B10, CABP, CACY, PRA
  • Links
    NCBI Gene ID: 6277
    neXtProt AC: NX_P06703

  • Chr Location
    1q21; chr1:153534600-153536241 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving S100a6
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052755 VEGA Gene Model | MGI Sequence Detail 11300 C57BL/6J ±  kb
transcript OTTMUST00000132089 VEGA | MGI Sequence Detail 783 Not Applicable  
polypeptide OTTMUSP00000070489 VEGA | MGI Sequence Detail 89 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    109 from dbSNP Build 137
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 170
    Genomic 3
    cDNA 167

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1721, MGI:88241
References
more
  • Summaries
    All 71
    Developmental Gene Expression 12
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:15754 Edwards DR, et al., Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements. Mol Cell Biol. 1985 Nov;5(11):3280-8
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory