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S100a6
Gene Detail
Symbol

Name
ID
S100a6
S100 calcium binding protein A6 (calcyclin)
MGI:1339467
STS
Synonyms
2A9, 5B10, Cacy, CALCYCLIN, PRA
Feature Type
protein coding gene
Genetic Map
Chromosome 3
39.35 cM, cytoband F1-F2
Detailed Genetic Map ± 1 cM


Mapping data(18)
Sequence Map
Chr3:90612894-90614414 bp, + strand
From NCBI annotation of GRCm38

  1521 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7925  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: S100A6
Protein SuperFamily: S-100 protein
Gene Tree: S100a6

Human
homologs
S100A6, S100 calcium binding protein A6
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6277
neXtProt AC: NX_P06703

Human Synonyms: 2A9, 5B10, CABP, CACY, PRA

Human Chr (Location): 1q21; chr1:153534600-153536241 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Interactions
S100a6 interacts with 28 markers (Mir7-1, Mir29c, Mir124a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process ion transmembrane transport
Component cytoplasm, cytosol, ...
Function calcium-dependent protein binding, calcium ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (16)    Tissues (14)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
RNA in situ 12
cDNA source data(164)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(170) Genomic(3) cDNA(167)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000001025 (Evidence)
Entrez Gene 20200 (Evidence)
UniGene 100144
DFCI TC1610338, TC1595642, TC1573037
DoTS DT.101147680, DT.537157, DT.97405040, DT.94340667, DT.94218156
PDB 4P2Y
Consensus CDS Project CCDS38506.1
International Mouse Phenotyping Consortium Status S100a6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 20200 NCBI Gene Model | MGI Sequence Detail 1521 C57BL/6J ±  kb
transcript NM_011313 RefSeq | MGI Sequence Detail 719 C57BL/6 
polypeptide P14069 UniProt | EBI | MGI Sequence Detail 89 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(2) : SNPs within 2kb(48 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
InterPro IPR001751 S100/Calbindin-D9k, conserved site
Protein Ontology PR:000014413 protein S100-A6
Graphical View of Protein Domain Structure
References
(Earliest) J:15754 Edwards DR, et al., Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements. Mol Cell Biol. 1985 Nov;5(11):3280-8
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(71)
Other
accession IDs
MGD-MRK-1721, MGI:88241

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory