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S100a9
Gene Detail
Symbol

Name
ID
S100a9
S100 calcium binding protein A9 (calgranulin B)
MGI:1338947
Synonyms
60B8Ag, BEE22, Cagb, GAGB, L1Ag, MRP14, p14
Feature Type
protein coding gene
Genetic Map
Chromosome 3
39.91 cM, cytoband F1-F2
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr3:90692632-90695721 bp, - strand
From VEGA annotation of GRCm38

  3090 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: S100A9
Protein SuperFamily: S-100 protein
Gene Tree: S100a9

Human
homologs
S100A9, S100 calcium binding protein A9
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 6280
neXtProt AC: NX_P06702

Human Synonyms: 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14

Human Chr (Location): 1q21; chr1:153357854-153361027 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(5) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for one null allele exhibit abnormal immune physiology.
 
Interactions
S100a9 interacts with 21 markers (Mir15a, Mir92-1, Mir184, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (14 records)
Data Summary: Results (138)    Tissues (21)    Images (31)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 124
Western blot 4
RT-PCR 10
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) Genomic(2) cDNA(24) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026669 (Evidence)
Ensembl Gene Model ENSMUSG00000056071 (Evidence)
Entrez Gene 20202 (Evidence)
UniGene 2128
DFCI TC1578387
DoTS DT.87069147, DT.103588551
NIA Mouse Gene Index U024303
Consensus CDS Project CCDS17543.1
International Mouse Phenotyping Consortium Status S100a9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026669 VEGA Gene Model | MGI Sequence Detail 3090 C57BL/6J ±  kb
transcript OTTMUST00000065991 VEGA | MGI Sequence Detail 512 Not Applicable 
polypeptide OTTMUSP00000032972 VEGA | MGI Sequence Detail 113 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(10 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
InterPro IPR001751 S100/Calbindin-D9k, conserved site
Protein Ontology PR:000014418 protein S100-A9
References
(Earliest) J:1255 Lagasse E, et al., Mouse MRP8 and MRP14, two intracellular calcium-binding proteins associated with the development of the myeloid lineage. Blood. 1992 Apr 15;79(8):1907-15
(Latest) J:222083 Wilson CL, et al., NFkappaB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun. 2015;6:6818
All references(94)
Other
accession IDs
MGD-MRK-1726, MGI:2139998, MGI:88245

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory