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Stau1
Gene Detail
Symbol

Name
ID
Stau1
staufen (RNA binding protein) homolog 1 (Drosophila)
MGI:1338864
Synonyms
5830401L18Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
87.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:166947549-166996299 bp, - strand
From VEGA annotation of GRCm38

  48751 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: STAU1
Gene Tree: Stau1

Human
homologs
STAU1, staufen double-stranded RNA binding protein 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 6780
neXtProt AC: NX_O95793

Human Synonyms: PPP1R150, STAU

Human Chr (Location): 20q13.1; chr20:49113339-49188370 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(72) : Gene trapped(70) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted allele exhibit hypoactivity and impaired dendrite outgrowth and spine formation.
 
Interactions
Stau1 interacts with 274 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (143)    Tissues (84)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 26
RNA in situ 85
Western blot 6
RT-PCR 26
cDNA source data(167)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase stau1 ; ZFIN stau1    NEW 
Molecular
reagents
All nucleic(175) cDNA(169) Primer pair(6)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000001134 (Evidence)
Ensembl Gene Model ENSMUSG00000039536 (Evidence)
Entrez Gene 20853 (Evidence)
UniGene 73276
DFCI TC1609687, TC1639062, TC1612969, TC1609567, TC1597602, TC1606804, TC1587346, TC1577120, TC1642237
DoTS DT.110686610, DT.101402372, DT.101263546, DT.101274988, DT.101233554, DT.91352764, DT.533253, DT.97391657, DT.94197205, DT.94175104
NIA Mouse Gene Index U023671
Consensus CDS Project CCDS17093.1, CCDS50800.1, CCDS50801.1, CCDS71197.1
International Mouse Phenotyping Consortium Status Stau1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001134 VEGA Gene Model | MGI Sequence Detail 48751 C57BL/6J ±  kb
transcript OTTMUST00000038584 VEGA | MGI Sequence Detail 2976 Not Applicable 
polypeptide OTTMUSP00000017268 VEGA | MGI Sequence Detail 495 Not Applicable 

For the selected sequences
All sequences(128) RefSeq(15) UniProt(16)
Polymorphisms
SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014720 Double-stranded RNA-binding-like domain
Protein Ontology PR:000015726 double-stranded RNA-binding protein Staufen homolog 1
References
(Earliest) J:53040 Wickham L, et al., Mammalian staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum. Mol Cell Biol. 1999 Mar;19(3):2220-30
(Latest) J:210040 Cho H, et al., SMG1 regulates adipogenesis via targeting of staufen1-mediated mRNA decay. Biochim Biophys Acta. 2013 Dec;1829(12):1276-87
All references(52)
Other
accession IDs
MGI:2139385, MGI:2139520, MGI:2441701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory