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Stau1
Gene Detail
 Symbol
Name
ID
Stau1
staufen (RNA binding protein) homolog 1 (Drosophila)
MGI:1338864
Synonyms 5830401L18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 2
87.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:166947549-166996299 bp, - strand
From VEGA annotation of GRCm38

  48751 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Gene Tree: Stau1

Human
homologs
Human Homolog STAU1, staufen double-stranded RNA binding protein 1
NCBI Gene ID 6780
neXtProt AC  NX_O95793
Human Synonyms  PPP1R150, STAU
Human Chr (Location)  20q13.1; chr20:49113339-49188370 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(72) : Gene trapped(70) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted allele exhibit hypoactivity and impaired dendrite outgrowth and spine formation.
 
Interactions
Stau1 interacts with 275 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process intracellular mRNA localization
Component cell body, cytoplasm, ...
Function double-stranded RNA binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (112)    Tissues (74)    Images (15)
Theiler Stages: 2, 3, 4, 5, 19, 21, 23, 24, 25, 26, 27, 28
Assay TypeResults
Immunohistochemistry 14
RNA in situ 72
Western blot 6
RT-PCR 20
cDNA source data(167)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(170) cDNA(167) Primer pair(3)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000001134 (Evidence)
Ensembl Gene ModelENSMUSG00000039536 (Evidence)
Entrez Gene20853 (Evidence)
UniGene73276
DFCITC1577120, TC1587346, TC1597602, TC1606804, TC1609567, TC1609687, TC1612969, TC1639062, TC1642237
DoTSDT.101233554, DT.101263546, DT.101274988, DT.101402372, DT.110686610, DT.533253, DT.91352764, DT.94175104, DT.94197205, DT.97391657
NIA Mouse Gene IndexU023671
Consensus CDS ProjectCCDS17093.1, CCDS50800.1, CCDS50801.1, CCDS71197.1
International Mouse Knockout Project StatusStau1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001134 VEGA Gene Model | MGI Sequence Detail 48751 C57BL/6J ±  kb
transcript OTTMUST00000038584 VEGA | MGI Sequence Detail 2976 Not Applicable 
polypeptide OTTMUSP00000017268 VEGA | MGI Sequence Detail 495 Not Applicable 

For the selected sequences
All sequences(125) RefSeq(13) UniProt(16)
Polymorphisms SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014720 Double-stranded RNA-binding-like domain
Protein Ontology PR:000015726 double-stranded RNA-binding protein Staufen homolog 1
References (Earliest) J:53040 Wickham L, et al., Mammalian staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum. Mol Cell Biol. 1999 Mar;19(3):2220-30
(Latest) J:202263 Jolly LA, et al., The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth. Hum Mol Genet. 2013 Dec 1;22(23):4673-87
All references(53)
Other
accession IDs
MGI:2139385, MGI:2139520, MGI:2441701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory