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Stau1
Gene Detail
Symbol

Name
ID
Stau1
staufen (RNA binding protein) homolog 1 (Drosophila)
MGI:1338864
Synonyms
5830401L18Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
87.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:166947549-166996299 bp, - strand
From VEGA annotation of GRCm38

  48751 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Gene Tree: Stau1

Human
homologs
Human Homolog   STAU1, staufen double-stranded RNA binding protein 1
NCBI Gene ID 6780
neXtProt AC  NX_O95793
Human Synonyms  PPP1R150, STAU
Human Chr (Location)  20q13.1; chr20:49113339-49188370 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(72) : Gene trapped(70) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted allele exhibit hypoactivity and impaired dendrite outgrowth and spine formation.
 
Interactions
Stau1 interacts with 274 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (143)    Tissues (84)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 26
RNA in situ 85
Western blot 6
RT-PCR 26
cDNA source data(167)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(175) cDNA(169) Primer pair(6)
Microarray probesets(7)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001134 VEGA Gene Model | MGI Sequence Detail 48751 C57BL/6J ±  kb
transcript OTTMUST00000038584 VEGA | MGI Sequence Detail 2976 Not Applicable 
polypeptide OTTMUSP00000017268 VEGA | MGI Sequence Detail 495 Not Applicable 

For the selected sequences
All sequences(127) RefSeq(15) UniProt(16)
Polymorphisms
SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014720 Double-stranded RNA-binding-like domain
Protein Ontology PR:000015726 double-stranded RNA-binding protein Staufen homolog 1
References
(Earliest) J:53040 Wickham L, et al., Mammalian staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum. Mol Cell Biol. 1999 Mar;19(3):2220-30
(Latest) J:210040 Cho H, et al., SMG1 regulates adipogenesis via targeting of staufen1-mediated mRNA decay. Biochim Biophys Acta. 2013 Dec;1829(12):1276-87
All references(53)
Other
accession IDs
MGI:2139385, MGI:2139520, MGI:2441701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory