Maz
Gene Detail

Symbol Name ID

Maz MYC-associated zinc finger protein (purine-binding transcription factor) MGI:1338823

Synonyms

Pur-1, PUR1, SAF-1, SAF-2

Feature Type

protein coding gene

Genetic Map

Chromosome 7

69.28 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:127022143-127026479 bp, - strand From Ensembl annotation of GRCm38   4337 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1787  Vertebrate Homology Class
1 human; 1 mouse; 1 rat

Gene Tree: Maz

Human homologs

Human Homolog		MAZ, MYC-associated zinc finger protein (purine-binding transcription factor)
NCBI Gene ID		4150
neXtProt AC		NX_P56270
Human Synonyms		Pur-1, PUR1, SAF-1, SAF-2, SAF-3, ZF87, Zif87, ZNF801
Human Chr (Location)		16p11.2; chr16:29817855-29822504 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(11) : Targeted(2) Gene trapped(9)

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, ...
Component	cytoplasm, nucleus
Function	chromatin binding, DNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (130)    Tissues (117)    Images (25)
Theiler Stages: 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	130

cDNA source data(154)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(157) cDNA(155) Primer pair(1) Other(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000030678 (Evidence)
Entrez Gene	17188 (Evidence)
UniGene	378964
DFCI	TC1601021, TC1618475
DoTS	DT.536959, DT.94275210
NIA Mouse Gene Index	U029274
Consensus CDS Project	CCDS40137.1
International Mouse Knockout Project Status	Maz

Sequences

Length	Strain/Species
genomic	ENSMUSG00000030678	Ensembl Gene Model | MGI Sequence Detail	4337	C57BL/6J
transcript	ENSMUST00000032916	Ensembl | MGI Sequence Detail	2365	Not Applicable
polypeptide	ENSMUSP00000032916	Ensembl | MGI Sequence Detail	477	Not Applicable

All sequences(27) RefSeq(3) UniProt(4)

Polymorphisms

SNPs(1 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007087	Zinc finger, C2H2
InterPro	IPR015880	Zinc finger, C2H2-like
InterPro	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology	PR:000010212	myc-associated zinc finger protein

References

(Earliest) J:54443 Kennedy GC, et al., Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells. Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11498-502
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)