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Maz Gene Detail
Summary
  • Symbol
    Maz
  • Name
    MYC-associated zinc finger protein (purine-binding transcription factor)
  • Synonyms
    Pur-1, PUR1, SAF-1, SAF-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338823
    NCBI Gene: 17188
  • Gene Overview
    MyGene.info: MAZ
Location & Maps
more
  • Sequence Map
    Chr7:127022130-127027037 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4908 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.28 cM, cytoband F4
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MAZ, MYC associated zinc finger protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MAZ, MYC associated zinc finger protein
    Orthology source: HomoloGene
  • Synonyms
    Pur-1, PUR1, SAF-1, SAF-2, SAF-3, ZF87, Zif87, ZNF801
  • Links
    NCBI Gene ID: 4150
    neXtProt AC: NX_P56270

  • Chr Location
    16p11.2; chr16:29806083-29811183 (+)  GRCh38.p2

Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    14
  • Gene trapped
    9
  • Targeted
    5
  • Genomic Mutations
    3 involving Maz
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058492 VEGA Gene Model | MGI Sequence Detail 4908 C57BL/6J ±  kb
transcript OTTMUST00000143626 VEGA | MGI Sequence Detail 2650 Not Applicable  
polypeptide OTTMUSP00000074872 VEGA | MGI Sequence Detail 493 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1 from dbSNP Build 142
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR007087 Zinc finger, C2H2
    IPR015880 Zinc finger, C2H2-like
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
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  • All nucleic 178
    cDNA 176
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Diseases 6
    Gene Ontology 9
    Phenotypes 13
  • Earliest
    J:54443 Kennedy GC, et al., Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells. Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11498-502
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory