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S100a11 Gene Detail
Summary
  • Symbol
    S100a11
  • Name
    S100 calcium binding protein A11
  • Synonyms
    cal, calgizzarin, Emap1, S100a14, S100c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338798
    NCBI Gene: 20195
  • Gene Overview
    MyGene.info: S100A11
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:93520496-93526288 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.51 cM, cytoband E-F
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338798
protein coding gene Chr3:93520488-93526288 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027536
protein coding gene Chr3:94023012-94028788 (+)
A/J MGP_AJ_G0027501
protein coding gene Chr3:91099223-91105105 (+)
AKR/J MGP_AKRJ_G0027469
protein coding gene Chr3:93208746-93214420 (+)
BALB/cJ MGP_BALBcJ_G0027510
protein coding gene Chr3:90852606-90858155 (+)
C3H/HeJ MGP_C3HHeJ_G0027248
protein coding gene Chr3:93417338-93424182 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027953
protein coding gene Chr3:97588737-97594558 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025303
protein coding gene Chr3:87692305-87697408 (+)
CAST/EiJ MGP_CASTEiJ_G0026696
protein coding gene Chr3:92867814-92874659 (+)
CBA/J MGP_CBAJ_G0027224
protein coding gene Chr3:100994583-101000392 (+)
DBA/2J MGP_DBA2J_G0027361
protein coding gene Chr3:90407367-90413191 (+)
FVB/NJ MGP_FVBNJ_G0027330
protein coding gene Chr3:88527118-88532962 (+)
LP/J MGP_LPJ_G0027471
protein coding gene Chr3:95274212-95281070 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027356
protein coding gene Chr3:107232714-107239669 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028012
protein coding gene Chr3:92924836-92930624 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0026245
protein coding gene Chr3:91287607-91293173 (+)
WSB/EiJ MGP_WSBEiJ_G0026779
protein coding gene Chr3:93306551-93312249 (+)



Homology
more
  • Human Ortholog
    S100A11, S100 calcium binding protein A11
  • Vertebrate Orthologs
    3
  • Human Ortholog
    S100A11, S100 calcium binding protein A11
    Orthology source: HGNC
  • Synonyms
    HEL-S-43, MLN70, S100C
  • Links
    NCBI Gene ID: 6282
    neXtProt AC: NX_P31949
    UniProt: P31949

  • Chr Location
    1q21.3; chr1:152032506-152037035 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice dwith disruptions in this gene display no obvious phenotype abnormalities other than reduced sperm counts in males.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20195 NCBI Gene Model | MGI Sequence Detail 5793 C57BL/6J ±  kb
transcript NM_016740 RefSeq | MGI Sequence Detail 504 C57BL/6  
polypeptide P50543 UniProt | EBI | MGI Sequence Detail 98 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 15
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-19682, MGI:102775, MGI:1353430
References
more
  • Summaries
    All 47
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:20657 Kao J, et al., Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II. J Biol Chem. 1994 Oct 7;269(40):25106-19
  • Latest
    J:265607 Naba A, et al., Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep. 2017 Jan 10;7:40495

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory