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Pex11a
Gene Detail
Symbol

Name
ID
Pex11a
peroxisomal biogenesis factor 11 alpha
MGI:1338788
Synonyms
PEX11alpha
Feature Type
protein coding gene
Genetic Map
Chromosome 7
45.12 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:79735957-79743131 bp, - strand
From VEGA annotation of GRCm38

  7175 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20829  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: peroxisomal membrane protein 11a
Gene Tree: Pex11a

Human
homologs
Human Homolog PEX11A, peroxisomal biogenesis factor 11 alpha
NCBI Gene ID 8800
neXtProt AC  NX_O75192
Human Synonyms  hsPEX11p, PEX11-ALPHA, PMP28
Human Chr (Location)  15q26.1; chr15:89681531-89690784 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
 
Mice homozygous for a knock-out allele exhibit minor abnormalities of the mitochondria and peroxisomes. Mice homozygous for a different knock-out allele exhibit increased body weight, hepatic steatosis and fewer, smaller peroxisomes in hepatocytes.
 
Interactions
Pex11a interacts with 164 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(50)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) cDNA(50) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000024967 (Evidence)
Ensembl Gene ModelENSMUSG00000030545 (Evidence)
Entrez Gene18631 (Evidence)
UniGene20615
DFCITC1603724, TC1603186, TC1584173, TC1605243
DoTSDT.101407792, DT.55122130, DT.531847
NIA Mouse Gene IndexU028748
Consensus CDS ProjectCCDS21386.1
International Mouse Knockout Project StatusPex11a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024967 VEGA Gene Model | MGI Sequence Detail 7175 C57BL/6J ±  kb
transcript OTTMUST00000061470 VEGA | MGI Sequence Detail 2241 Not Applicable 
polypeptide OTTMUSP00000030153 VEGA | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008733 Peroxisomal biogenesis factor 11
Protein Ontology PR:000012555 peroxisomal membrane protein 11A
References
(Earliest) J:50862 Schrader M, et al., Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli. J Biol Chem. 1998 Nov 6;273(45):29607-14
(Latest) J:195940 Weng H, et al., Pex11alpha deficiency impairs peroxisome elongation and division and contributes to nonalcoholic fatty liver in mice. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E187-96
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory