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Sec22b
Gene Detail
Symbol

Name
ID
Sec22b
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
MGI:1338759
Synonyms
4930564D15Rik, ERS-24, Sec22l1
Feature Type
protein coding gene
Genetic Map
Chromosome 3
42.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:97901190-97923276 bp, + strand
From VEGA annotation of GRCm38

  22087 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3597  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: SEC22B
Gene Tree: Sec22b

Human
homologs
SEC22B, SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9554
neXtProt AC: NX_O75396

Human Synonyms: ERS-24, SEC22L1

Human Chr (Location): 1q21.1; chr1:120155942-120176521 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sec22b interacts with 267 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process ER to Golgi vesicle-mediated transport, positive regulation of protein catabolic process, ...
Component cell, cytoplasm, ...
Function SNAP receptor activity, SNARE binding, ...
External Resources: FuncBase
Expression
cDNA source data(17)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sec22b ; ZFIN sec22bb    NEW 
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000028867 (Evidence)
Ensembl Gene Model ENSMUSG00000027879 (Evidence)
Entrez Gene 20333 (Evidence)
DFCI TC1576907, TC1644889, TC1676016
DoTS DT.111059069, DT.488199, DT.91339855, DT.488422
NIA Mouse Gene Index U359432, U003619
PDB 1IFQ
Consensus CDS Project CCDS17658.1
International Mouse Phenotyping Consortium Status Sec22b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028867 VEGA Gene Model | MGI Sequence Detail 22087 C57BL/6J ±  kb
transcript OTTMUST00000071496 VEGA | MGI Sequence Detail 2810 Not Applicable 
polypeptide OTTMUSP00000036640 VEGA | MGI Sequence Detail 215 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(151 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010908 Longin domain
InterPro IPR011012 Longin-like domain
InterPro IPR001388 Synaptobrevin
Protein Ontology PR:000014584 vesicle-trafficking protein SEC22b
References
(Earliest) J:46012 Hay JC, et al., Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell. 1997 Apr 4;89(1):149-58
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGI:1922615, MGI:2139737, MGI:2140084, MGI:3035211

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory