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Theg Gene Detail
Summary
  • Symbol
    Theg
  • Name
    testicular haploid expressed gene
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338756
    NCBI Gene: 21830
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79576477-79587136 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband B5-C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338756
protein coding gene Chr10:79576379-79587331 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017446
protein coding gene Chr10:80107568-80121748 (-)
A/J MGP_AJ_G0017424
protein coding gene Chr10:77326664-77337609 (-)
AKR/J MGP_AKRJ_G0017385
protein coding gene Chr10:79427264-79440310 (-)
BALB/cJ MGP_BALBcJ_G0017386
protein coding gene Chr10:77553092-77564575 (-)
C3H/HeJ MGP_C3HHeJ_G0017209
protein coding gene Chr10:79534432-79546739 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017840
protein coding gene Chr10:82877792-82892569 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015528
protein coding gene Chr10:73553171-73564080 (-)
CAST/EiJ MGP_CASTEiJ_G0016776
protein coding gene Chr10:79710754-79721714 (-)
CBA/J MGP_CBAJ_G0017181
protein coding gene Chr10:86101301-86115869 (-)
DBA/2J MGP_DBA2J_G0017287
protein coding gene Chr10:76543527-76554983 (-)
FVB/NJ MGP_FVBNJ_G0017281
protein coding gene Chr10:75703626-75714673 (-)
LP/J MGP_LPJ_G0017358
protein coding gene Chr10:80584405-80600120 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017307
protein coding gene Chr10:88085732-88097517 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017881
protein coding gene Chr10:79410661-79421505 (-)
PWK/PhJ MGP_PWKPhJ_G0016557
protein coding gene Chr10:76399950-76411076 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016346
protein coding gene Chr10:78389534-78398405 (-)
WSB/EiJ MGP_WSBEiJ_G0016836
protein coding gene Chr10:79436765-79448774 (-)



Homology
more
  • Human Ortholog
    THEG, theg spermatid protein
  • Vertebrate Orthologs
    7
  • Human Ortholog
    THEG, theg spermatid protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT56, THEG1
  • Links
    NCBI Gene ID: 51298
    neXtProt AC: NX_Q9P2T0
    UniProt: Q9P2T0

  • Chr Location
    19p13.3; chr19:362057-376693 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 3 alleles in 4 genetic backgrounds
    1 images
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Males homozygotes for a transgenic insertional mutation are sterile due to a block in spermiogenesis. Testis weights are reduced, and mutants exhibit multiple abnormalities in elongated spermatids in the seminiferous tubule lumen.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21830 NCBI Gene Model | MGI Sequence Detail 10660 C57BL/6J ±  kb
transcript NM_011583 RefSeq | MGI Sequence Detail 1249 C57BL/6  
polypeptide Q9JMB1 UniProt | EBI | MGI Sequence Detail 375 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory