Tfg
Gene Detail

Symbol Name ID

Tfg Trk-fused gene MGI:1338041

Feature Type

protein coding gene

Genetic Map

Chromosome 16

34.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr16:56690332-56717450 bp, - strand From VEGA annotation of GRCm38   27119 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4426  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tfg

Human homologs

Human Homolog		TFG, TRK-fused gene
NCBI Gene ID		10342
neXtProt AC		NX_Q92734
Human Synonyms		HMSNP, SPG57, TF6, TRKT3
Human Chr (Location)		3q12.2; chr3:100428134-100467811 (+)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human TFG

Alleles and phenotypes

All alleles(19) : Targeted(1) Gene trapped(18)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction
Component	cellular_component
Function	identical protein binding, protein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (14)    Tissues (13)   
Theiler Stages: 10, 18, 22, 23, 25

Assay Type	Results
RNA in situ	10
Northern blot	4

cDNA source data(129)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(129) cDNA(129)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000026667 (Evidence)
Ensembl Gene Model	ENSMUSG00000022757 (Evidence)
Entrez Gene	21787 (Evidence)
UniGene	425970
DFCI	TC1572104, TC1596502, TC1596819, TC1604378, TC1645170, TC1699338, TC1718268
DoTS	DT.101358804, DT.101380206, DT.492285, DT.94275270
NIA Mouse Gene Index	U037119
Consensus CDS Project	CCDS28224.1
International Mouse Knockout Project Status	Tfg

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026667	VEGA Gene Model | MGI Sequence Detail	27119	C57BL/6J
transcript	OTTMUST00000065984	VEGA | MGI Sequence Detail	1945	Not Applicable
polypeptide	OTTMUSP00000032965	VEGA | MGI Sequence Detail	397	Not Applicable

All sequences(91) RefSeq(4) UniProt(9)

Polymorphisms

SNPs(119 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000270	Phox/Bem1p
Protein Ontology	PR:000016277	protein TFG

References

(Earliest) J:54190 Mencinger M, et al., Characterization of TFG in mus musculus and Caenorhabditis elegans. Biochem Biophys Res Commun. 1999 Apr 2;257(1):67-73
(Latest) J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
All references(34)

Other accession IDs

MGI:2146382