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Rbm6 Gene Detail
Summary
  • Symbol
    Rbm6
  • Name
    RNA binding motif protein 6
  • Synonyms
    Def-3, g16, NY-LU-12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338037
    NCBI Gene: 19654
  • Gene Overview
    MyGene.info: RBM6
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:107773559-107872822 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.07 cM, cytoband F1-F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338037
protein coding gene Chr9:107773559-107873237 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035270
protein coding gene Chr9:109676570-109786197 (-)
A/J MGP_AJ_G0035249
protein coding gene Chr9:105674340-105777024 (-)
AKR/J MGP_AKRJ_G0035181
protein coding gene Chr9:108312150-108415822 (-)
BALB/cJ MGP_BALBcJ_G0035243
protein coding gene Chr9:105343461-105447378 (-)
C3H/HeJ MGP_C3HHeJ_G0034953
protein coding gene Chr9:108707227-108816275 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035763
protein coding gene Chr9:112653598-112754001 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032661
protein coding gene Chr9:103103549-103203583 (-)
CAST/EiJ MGP_CASTEiJ_G0034264
protein coding gene Chr9:108661914-108770637 (-)
CBA/J MGP_CBAJ_G0034921
protein coding gene Chr9:116628882-116743267 (-)
DBA/2J MGP_DBA2J_G0035082
protein coding gene Chr9:105133899-105231442 (-)
FVB/NJ MGP_FVBNJ_G0035030
protein coding gene Chr9:103896160-103997439 (-)
LP/J MGP_LPJ_G0035158
protein coding gene Chr9:109868753-109983571 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035069
protein coding gene Chr9:118240001-118349608 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035784
protein coding gene Chr9:108588039-108693807 (-)
PWK/PhJ MGP_PWKPhJ_G0033971
protein coding gene Chr9:105450733-105552133 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033806
protein coding gene Chr9:108640084-108755201 (-)
WSB/EiJ MGP_WSBEiJ_G0034385
protein coding gene Chr9:108465688-108574691 (-)



Homology
more
  • Human Ortholog
    RBM6, RNA binding motif protein 6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RBM6, RNA binding motif protein 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    3G2, DEF3, DEF-3, g16, HLC-11, NY-LU-12
  • Links
    NCBI Gene ID: 10180
    neXtProt AC: NX_P78332
    UniProt: P78332

  • Chr Location
    3p21.31; chr3:49940038-50077252 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19654 NCBI Gene Model | MGI Sequence Detail 99264 C57BL/6J ±  kb
transcript NM_029169 RefSeq | MGI Sequence Detail 3991 C57BL/6  
polypeptide NP_035381 RefSeq | MGI Sequence Detail 1118 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    Genomic 1
    cDNA 112
    Primer pair 1
    Other 1

    Microarray probesets 6
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:54520 Drabkin HA, et al., DEF-3(g16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC. Oncogene. 1999 Apr 22;18(16):2589-97
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory