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Capn7
Gene Detail
Symbol

Name
ID
Capn7
calpain 7
MGI:1338030
Synonyms
PalBH
Feature Type
protein coding gene
Genetic Map
Chromosome 14
19.10 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:31336638-31371986 bp, + strand
From VEGA annotation of GRCm38

  35349 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7651  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CAPN7
Gene Tree: Capn7

Human
homologs
CAPN7, calpain 7
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23473
neXtProt AC: NX_Q9Y6W3

Human Synonyms: CALPAIN7, PALBH

Human Chr (Location): 3p24; chr3:15206226-15252916 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(5) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene frequently die before weaning. Survivors display reduced body weight.
 
Interactions
Capn7 interacts with 373 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (165)    Tissues (110)    Images (47)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 34
In situ reporter (knock in) 93
RT-PCR 38
cDNA source data(84)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase capn7    NEW 
Molecular
reagents
All nucleic(85) cDNA(84) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000027910 (Evidence)
Ensembl Gene Model ENSMUSG00000021893 (Evidence)
Entrez Gene 12339 (Evidence)
UniGene 201535
DFCI TC1575049
DoTS DT.101239720, DT.491452, DT.97347864
NIA Mouse Gene Index U043389
EC 3.4.22.-
Consensus CDS Project CCDS26911.1
International Mouse Phenotyping Consortium Status Capn7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027910 VEGA Gene Model | MGI Sequence Detail 35349 C57BL/6J ±  kb
transcript OTTMUST00000069127 VEGA | MGI Sequence Detail 3648 Not Applicable 
polypeptide OTTMUSP00000035062 VEGA | MGI Sequence Detail 813 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(435 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007330 MIT
InterPro IPR001300 Peptidase C2, calpain, catalytic domain
InterPro IPR022683 Peptidase C2, calpain, domain III
InterPro IPR022684 Peptidase C2, calpain family
InterPro IPR022682 Peptidase C2, calpain, large subunit, domain III
Protein Ontology PR:000005019 calpain-7
References
(Earliest) J:53883 Franz T, et al., Capn7: a highly divergent vertebrate calpain with a novel C-terminal domain. Mamm Genome. 1999 Mar;10(3):318-21
(Latest) J:157819 Shimogori T, et al., A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
All references(33)
Other
accession IDs
MGI:2145742

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory