About   Help   FAQ
Tom1 Gene Detail
Summary
  • Symbol
    Tom1
  • Name
    target of myb1 trafficking protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338026
    NCBI Gene: 21968
  • Gene Overview
    MyGene.info: TOM1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:75033705-75070121 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 35.57 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    221 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338026
protein coding gene Chr8:75033658-75070121 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033794
protein coding gene Chr8:75483183-75524102 (+)
A/J MGP_AJ_G0033776
protein coding gene Chr8:72518842-72555075 (+)
AKR/J MGP_AKRJ_G0033703
protein coding gene Chr8:74727578-74768563 (+)
BALB/cJ MGP_BALBcJ_G0033770
protein coding gene Chr8:72615444-72655724 (+)
C3H/HeJ MGP_C3HHeJ_G0033479
protein coding gene Chr8:75285510-75324234 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034290
protein coding gene Chr8:78409442-78446947 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031231
protein coding gene Chr8:66788941-66823789 (+)
CAST/EiJ MGP_CASTEiJ_G0032808
protein coding gene Chr8:74561739-74599216 (+)
CBA/J MGP_CBAJ_G0033458
protein coding gene Chr8:81164043-81209157 (+)
DBA/2J MGP_DBA2J_G0033612
protein coding gene Chr8:72206353-72243779 (+)
FVB/NJ MGP_FVBNJ_G0033557
protein coding gene Chr8:71283359-71319578 (+)
LP/J MGP_LPJ_G0033701
protein coding gene Chr8:75610411-75651173 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033600
protein coding gene Chr8:83725747-83763226 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034307
protein coding gene Chr8:74693316-74732971 (+)
PWK/PhJ MGP_PWKPhJ_G0032514
protein coding gene Chr8:71476444-71513924 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032352
protein coding gene Chr8:73583893-73620229 (+)
WSB/EiJ MGP_WSBEiJ_G0032923
protein coding gene Chr8:74999545-75036848 (+)



Homology
more
  • Human Ortholog
    TOM1, target of myb1 membrane trafficking protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TOM1, target of myb1 membrane trafficking protein
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10043
    neXtProt AC: NX_O60784
    UniProt: O60784

  • Chr Location
    22q12.3; chr22:35299275-35347994 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042870 Ensembl Gene Model | MGI Sequence Detail 36417 C57BL/6J ±  kb
transcript ENSMUST00000078847 Ensembl | MGI Sequence Detail 1769 Not Applicable  
polypeptide ENSMUSP00000077891 Ensembl | MGI Sequence Detail 516 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 2
    cDNA 15
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:54916 Seroussi E, et al., TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM. Genomics. 1999 May 1;57(3):380-8
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory