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Bex2 Gene Detail
Summary
  • Symbol
    Bex2
  • Name
    brain expressed X-linked 2
  • Synonyms
    Bex1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338017
    NCBI Gene: 12069
  • Gene Overview
    MyGene.info: BEX1
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:136066565-136068236 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 57.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    17
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338017
protein coding gene ChrX:136066564-136068236 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036092
protein coding gene ChrX:133422172-133423844 (-)
A/J MGP_AJ_G0036073
protein coding gene ChrX:132826243-132827964 (-)
AKR/J MGP_AKRJ_G0035999
protein coding gene ChrX:137090882-137092554 (-)
BALB/cJ MGP_BALBcJ_G0036061
protein coding gene ChrX:131214504-131216176 (-)
C3H/HeJ MGP_C3HHeJ_G0035771
protein coding gene ChrX:133414638-133416500 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036584
protein coding gene ChrX:137259102-137260698 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033414
protein coding gene ChrX:124823584-124824689 (-)
CAST/EiJ MGP_CASTEiJ_G0035060
protein coding gene ChrX:114338983-114340632 (-)
CBA/J MGP_CBAJ_G0035747
protein coding gene ChrX:141476418-141481687 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0035838
protein coding gene ChrX:131337687-131339617 (-)
LP/J MGP_LPJ_G0035996
protein coding gene ChrX:134351359-134353031 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035872
protein coding gene ChrX:148868001-148869145 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036621
protein coding gene ChrX:132777000-132778880 (-)
PWK/PhJ MGP_PWKPhJ_G0034751
protein coding gene ChrX:111252216-111254270 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034582
protein coding gene ChrX:114989367-114991926 (-)
WSB/EiJ MGP_WSBEiJ_G0035193
protein coding gene ChrX:131114650-131116322 (-)



Homology
more
  • Human Ortholog
    BEX1, brain expressed X-linked 1
  • Vertebrate Orthologs
    4
  • Human Ortholog
    BEX1, brain expressed X-linked 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BEX2, HBEX2, HGR74-h
  • Links
    NCBI Gene ID: 55859
    neXtProt AC: NX_Q9HBH7
    UniProt: Q9HBH7

  • Chr Location
    Xq21-q23; chrX:103062653-103064240 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12069 NCBI Gene Model | MGI Sequence Detail 1672 C57BL/6J ±  kb
    transcript NM_009749 RefSeq | MGI Sequence Detail 902 C57BL/6  
    polypeptide Q9WTZ8 UniProt | EBI | MGI Sequence Detail 129 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR007623 Brain-expressed X-linked protein
      IPR021156 Transcription elongation factor A-like/Brain expressed X-linked
    Molecular
    Reagents
    less
    • All nucleic 48
      cDNA 46
      Primer pair 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2147946
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 6
      Diseases 1
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:54406 Brown AL, et al., Bex1, a gene with increased expression in parthenogenetic embryos, is a member of a novel gene family on the mouse X chromosome. Hum Mol Genet. 1999 Apr;8(4):611-9
    • Latest
      J:225965 Hu Z, et al., Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis. J Biol Chem. 2015 Oct 16;290(42):25756-65

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory