About   Help   FAQ
Auh
Gene Detail
 Symbol
Name
ID
Auh
AU RNA binding protein/enoyl-coenzyme A hydratase
MGI:1338011
Synonyms W91705
Feature Type protein coding gene
Genetic Map
Chromosome 13
27.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:52835119-52929681 bp, - strand
From VEGA annotation of GRCm38

  94563 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1284  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: AU-specific RNA-binding protein AUH
Gene Tree: Auh

Human
homologs
Human Homolog AUH, AU RNA binding protein/enoyl-CoA hydratase
NCBI Gene ID 549
neXtProt AC  NX_Q13825
Human Chr (Location)  9q22.31; chr9:91213815-91361933 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human AUH
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Auh interacts with 332 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process branched-chain amino acid catabolic process, metabolic process, ...
Component mitochondrion
Function catalytic activity, enoyl-CoA hydratase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(62)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(64) cDNA(63) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000026355 (Evidence)
Ensembl Gene ModelENSMUSG00000021460 (Evidence)
Entrez Gene11992 (Evidence)
UniGene252034
DFCITC1579130, TC1587566, TC1627002, TC1638392, TC1709745, TC1710806
DoTSDT.101254311, DT.110971070, DT.40158776, DT.488988, DT.97398403
NIA Mouse Gene IndexU034783
EC4.2.1.18
Consensus CDS ProjectCCDS26518.1
International Mouse Knockout Project StatusAuh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026355 VEGA Gene Model | MGI Sequence Detail 94563 C57BL/6J ±  kb
transcript OTTMUST00000065168 VEGA | MGI Sequence Detail 1320 Not Applicable 
polypeptide OTTMUSP00000032438 VEGA | MGI Sequence Detail 314 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(9) UniProt(6)
Polymorphisms SNPs within 2kb(696 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014748 Crontonase, C-terminal
InterPro IPR001753 Crotonase superfamily
InterPro IPR018376 Enoyl-CoA hydratase/isomerase, conserved site
Protein Ontology PR:000004513 methylglutaconyl-CoA hydratase, mitochondrial
References (Earliest) J:53502 Brennan LE, et al., Characterisation and mitochondrial localisation of AUH, an AU-specific RNA-binding enoyl-CoA hydratase. Gene. 1999 Mar 4;228(1-2):85-91
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:2145486, MGI:2145548

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory