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Auh
Gene Detail
Symbol

Name
ID
Auh
AU RNA binding protein/enoyl-coenzyme A hydratase
MGI:1338011
Synonyms
W91705
Feature Type
protein coding gene
Genetic Map
Chromosome 13
27.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:52835119-52929681 bp, - strand
From VEGA annotation of GRCm38

  94563 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1284  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AUH
Protein SuperFamily: AU-specific RNA-binding protein AUH
Gene Tree: Auh

Human
homologs
AUH, AU RNA binding protein/enoyl-CoA hydratase
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 549
neXtProt AC: NX_Q13825

Human Chr (Location): 9q22.31; chr9:91213815-91361939 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human AUH

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Auh interacts with 332 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process branched-chain amino acid catabolic process, metabolic process, ...
Component mitochondrion
Function catalytic activity, enoyl-CoA hydratase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(62)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase auh ; ZFIN auh    NEW 
Molecular
reagents
All nucleic(64) cDNA(63) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000026355 (Evidence)
Ensembl Gene Model ENSMUSG00000021460 (Evidence)
Entrez Gene 11992 (Evidence)
UniGene 252034
DFCI TC1579130, TC1587566, TC1710806, TC1627002, TC1709745, TC1638392
DoTS DT.97398403, DT.488988, DT.110971070, DT.101254311, DT.40158776
NIA Mouse Gene Index U034783
EC 4.2.1.18
Consensus CDS Project CCDS26518.1
International Mouse Phenotyping Consortium Status Auh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026355 VEGA Gene Model | MGI Sequence Detail 94563 C57BL/6J ±  kb
transcript OTTMUST00000065168 VEGA | MGI Sequence Detail 1320 Not Applicable 
polypeptide OTTMUSP00000032438 VEGA | MGI Sequence Detail 314 Not Applicable 

For the selected sequences
All sequences(87) RefSeq(8) UniProt(6)
Polymorphisms
SNPs within 2kb(696 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014748 Crontonase, C-terminal
InterPro IPR001753 Crotonase superfamily
InterPro IPR018376 Enoyl-CoA hydratase/isomerase, conserved site
Protein Ontology PR:000004513 methylglutaconyl-CoA hydratase, mitochondrial
References
(Earliest) J:53502 Brennan LE, et al., Characterisation and mitochondrial localisation of AUH, an AU-specific RNA-binding enoyl-CoA hydratase. Gene. 1999 Mar 4;228(1-2):85-91
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGI:2145486, MGI:2145548

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory