Auh
Gene Detail

Symbol Name ID

Auh AU RNA binding protein/enoyl-coenzyme A hydratase MGI:1338011

Synonyms

W91705

Feature Type

protein coding gene

Genetic Map

Chromosome 13

27.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr13:52835119-52929681 bp, - strand From VEGA annotation of GRCm38   94563 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1284  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: AU-specific RNA-binding protein AUH
Gene Tree: Auh

Human homologs

Human Homolog		AUH, AU RNA binding protein/enoyl-CoA hydratase
NCBI Gene ID		549
neXtProt AC		NX_Q13825
Human Chr (Location)		9q22.31; chr9:93976097-94124206 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human AUH

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	branched-chain amino acid catabolic process, metabolic process, ...
Component	mitochondrion
Function	catalytic activity, enoyl-CoA hydratase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(62)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(64) cDNA(63) Primer pair(1)
Microarray probesets(8)

Other database links

VEGA Gene Model	OTTMUSG00000026355 (Evidence)
Ensembl Gene Model	ENSMUSG00000021460 (Evidence)
Entrez Gene	11992 (Evidence)
UniGene	252034
DFCI	TC1579130, TC1587566, TC1627002, TC1638392, TC1709745, TC1710806
DoTS	DT.101254311, DT.110971070, DT.40158776, DT.488988, DT.97398403
NIA Mouse Gene Index	U034783
EC	4.2.1.18
Consensus CDS Project	CCDS26518.1
International Mouse Knockout Project Status	Auh

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026355	VEGA Gene Model | MGI Sequence Detail	94563	C57BL/6J
transcript	OTTMUST00000065168	VEGA | MGI Sequence Detail	1320	Not Applicable
polypeptide	OTTMUSP00000032438	VEGA | MGI Sequence Detail	314	Not Applicable

All sequences(81) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(611 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR014748	Crontonase, C-terminal
InterPro	IPR001753	Crotonase, core
InterPro	IPR018376	Enoyl-CoA hydratase/isomerase, conserved site
Protein Ontology	PR:000004513	methylglutaconyl-CoA hydratase, mitochondrial

References

(Earliest) J:53502 Brennan LE, et al., Characterisation and mitochondrial localisation of AUH, an AU-specific RNA-binding enoyl-CoA hydratase. Gene. 1999 Mar 4;228(1-2):85-91
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Other accession IDs

MGI:2145486, MGI:2145548