About   Help   FAQ
Auh Gene Detail
Summary
  • Symbol
    Auh
  • Name
    AU RNA binding protein/enoyl-coenzyme A hydratase
  • Synonyms
    W91705
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338011
    NCBI Gene: 11992
Location & Maps
more
  • Sequence Map
    Chr13:52835119-52929681 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      94563 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 27.68 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    AUH, AU RNA binding methylglutaconyl-CoA hydratase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AUH, AU RNA binding methylglutaconyl-CoA hydratase
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 549
    neXtProt AC: NX_Q13825

  • Chr Location
    9q22.31; chr9:91213815-91361939 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human AUH associations

Human Disease Mouse Models
       3-methylglutaconic Aciduria, Type I; MGCA1   OMIM: 250950
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Auh
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026355 VEGA Gene Model | MGI Sequence Detail 94563 C57BL/6J ±  kb
transcript OTTMUST00000065168 VEGA | MGI Sequence Detail 1320 Not Applicable  
polypeptide OTTMUSP00000032438 VEGA | MGI Sequence Detail 314 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    694 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 63
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:2145486, MGI:2145548
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:53502 Brennan LE, et al., Characterisation and mitochondrial localisation of AUH, an AU-specific RNA-binding enoyl-CoA hydratase. Gene. 1999 Mar 4;228(1-2):85-91
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory