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Gdap1
Gene Detail
 Symbol
Name
ID
Gdap1
ganglioside-induced differentiation-associated-protein 1
MGI:1338002
Feature Type protein coding gene
Genetic Map
Chromosome 1
5.21 cM, cytoband A4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:17145362-17164271 bp, + strand
From VEGA annotation of GRCm38

  18910 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40713  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Gdap1

Human
homologs
Human Homolog GDAP1, ganglioside induced differentiation associated protein 1
NCBI Gene ID 54332
neXtProt AC  NX_Q8TB36
Human Synonyms  CMT4, CMT4A, CMTRIA
Human Chr (Location)  8q21.11; chr8:74350383-74367110 (+)  GRCh38
Disease Associations  (4) Diseases Associated with Human GDAP1
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix )
Interactions
Gdap1 interacts with 337 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process mitochondrial fission, protein targeting to mitochondrion, ...
Component cytoplasm, integral component of membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (38)    Tissues (29)    Images (4)
Theiler Stages: 8, 10, 12, 20, 21, 23, 24, 28
Assay TypeResults
RNA in situ 14
Northern blot 15
RT-PCR 9
cDNA source data(41)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(46) cDNA(44) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000022300 (Evidence)
Ensembl Gene ModelENSMUSG00000025777 (Evidence)
Entrez Gene14545 (Evidence)
UniGene18218
DFCITC1579847, TC1587624
DoTSDT.40144313, DT.60100330
NIA Mouse Gene IndexU000076
Consensus CDS ProjectCCDS14834.1
International Mouse Knockout Project StatusGdap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022300 VEGA Gene Model | MGI Sequence Detail 18910 C57BL/6J ±  kb
transcript OTTMUST00000053130 VEGA | MGI Sequence Detail 3949 Not Applicable 
polypeptide OTTMUSP00000025245 VEGA | MGI Sequence Detail 358 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(72 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010987 Glutathione S-transferase, C-terminal-like
InterPro IPR004045 Glutathione S-transferase, N-terminal
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000007912 ganglioside-induced differentiation-associated protein 1
References (Earliest) J:54635 Liu H, et al., Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene. J Neurochem. 1999 May;72(5):1781-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory