Gdap1
Gene Detail

Symbol Name ID

Gdap1 ganglioside-induced differentiation-associated-protein 1 MGI:1338002

Feature Type

protein coding gene

Genetic Map

Chromosome 1

5.21 cM, cytoband A4
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:17145362-17164271 bp, + strand From VEGA annotation of GRCm38   18910 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40713  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Gdap1

Human homologs

Human Homolog		GDAP1, ganglioside induced differentiation associated protein 1
NCBI Gene ID		54332
neXtProt AC		NX_Q8TB36
Human Synonyms		CMT4, CMT4A, CMTRIA
Human Chr (Location)		8q21.11; chr8:75262618-75279345 (+)  GRCh37.p10
Disease Associations		(4) Diseases Associated with Human GDAP1

Alleles and phenotypes

All alleles(5) : Targeted(5)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	mitochondrial fission, protein targeting to mitochondrion, ...
Component	cytoplasm, integral to membrane, ...
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (38)    Tissues (29)    Images (4)
Theiler Stages: 8, 10, 12, 20, 21, 23, 24, 28

Assay Type	Results
RNA in situ	14
Northern blot	15
RT-PCR	9

cDNA source data(40)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(45) cDNA(43) Primer pair(1) Other(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000022300 (Evidence)
Ensembl Gene Model	ENSMUSG00000025777 (Evidence)
Entrez Gene	14545 (Evidence)
UniGene	18218
DFCI	TC1579847, TC1587624
DoTS	DT.40144313, DT.60100330
NIA Mouse Gene Index	U000076
Consensus CDS Project	CCDS14834.1
International Mouse Knockout Project Status	Gdap1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022300	VEGA Gene Model | MGI Sequence Detail	18910	C57BL/6J
transcript	OTTMUST00000053130	VEGA | MGI Sequence Detail	3949	Not Applicable
polypeptide	OTTMUSP00000025245	VEGA | MGI Sequence Detail	358	Not Applicable

All sequences(31) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(49 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017933	Glutathione S-transferase/chloride channel, C-terminal
InterPro	IPR010987	Glutathione S-transferase, C-terminal-like
InterPro	IPR004045	Glutathione S-transferase, N-terminal
InterPro	IPR012336	Thioredoxin-like fold
Protein Ontology	PR:000007912	ganglioside-induced differentiation-associated protein 1

References

(Earliest) J:54635 Liu H, et al., Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene. J Neurochem. 1999 May;72(5):1781-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)