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Ap3s2
Gene Detail
Symbol

Name
ID
Ap3s2
adaptor-related protein complex 3, sigma 2 subunit
MGI:1337060
Synonyms
[s]3B, sigma 3B
Feature Type
protein coding gene
Genetic Map
Chromosome 7
45.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:79875332-79920640 bp, - strand
From Ensembl annotation of GRCm38

  45309 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:100592  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AP3S2
Protein SuperFamily: adaptor protein complex, sigma subunit
Gene Tree: Ap3s2

Human
homologs
AP3S2, adaptor-related protein complex 3, sigma 2 subunit
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10239
neXtProt AC: NX_P59780

Human Synonyms: AP3S3, sigma3b

Human Chr (Location): 15q26.1; chr15:89830599-89894385 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ap3s2 interacts with 408 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process anterograde axon cargo transport, anterograde synaptic vesicle transport, ...
Component AP-3 adaptor complex, cell, ...
Function protein transporter activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (53)    Tissues (9)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 53
cDNA source data(121)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ap3s2    NEW 
Molecular
reagents
All nucleic(121) cDNA(121)
Microarray probesets(10)
Other database
links
Ensembl Gene Model ENSMUSG00000063801 (Evidence)
Entrez Gene 11778 (Evidence)
UniGene 220173
DFCI TC1579870, TC1591640, TC1614889, TC1641056, TC1629855, TC1661280
DoTS DT.101735883, DT.101341162
NIA Mouse Gene Index U162775, U113718
Consensus CDS Project CCDS21389.1
International Mouse Phenotyping Consortium Status Ap3s2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063801 Ensembl Gene Model | MGI Sequence Detail 45309 C57BL/6J ±  kb
transcript ENSMUST00000075657 Ensembl | MGI Sequence Detail 5797 Not Applicable 
polypeptide ENSMUSP00000075082 Ensembl | MGI Sequence Detail 193 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(215 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016635 Adaptor protein complex, sigma subunit
InterPro IPR022775 AP complex, mu/sigma subunit
InterPro IPR000804 Clathrin adaptor complex, small chain
InterPro IPR011012 Longin-like domain
Protein Ontology PR:000004110 AP-3 complex subunit sigma-2
References
(Earliest) J:20036 Simpson F, et al., Characterization of the adaptor-related protein complex, AP-3. J Cell Biol. 1997 May 19;137(4):835-45
(Latest) J:187545 Larimore J, et al., The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse. Mol Biol Cell. 2011 Dec;22(24):4854-67
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory