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Trim26 Gene Detail
Summary
  • Symbol
    Trim26
  • Name
    tripartite motif-containing 26
  • Synonyms
    Zfp173
  • Feature Type
    protein coding gene
  • IDs
    MGI:1337056
    NCBI Gene: 22670
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:36837134-36859398 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1337056
protein coding gene Chr17:36837123-36859398 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023682
protein coding gene Chr17:37187003-37209128 (+)
A/J MGP_AJ_G0023640
protein coding gene Chr17:36015515-36038650 (+)
AKR/J MGP_AKRJ_G0023611
protein coding gene Chr17:36446450-36473042 (+)
BALB/cJ MGP_BALBcJ_G0023647
protein coding gene Chr17:36257393-36279806 (+)
C3H/HeJ MGP_C3HHeJ_G0023409
protein coding gene Chr17:36963330-36986834 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024085
protein coding gene Chr17:38786090-38808095 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021553
protein coding gene Chr17:33829002-33851566 (+)
CAST/EiJ MGP_CASTEiJ_G0022894
protein coding gene Chr17:37092040-37115265 (+)
CBA/J MGP_CBAJ_G0023386
protein coding gene Chr17:40295570-40322926 (+)
DBA/2J MGP_DBA2J_G0023511
protein coding gene Chr17:35408739-35431057 (+)
FVB/NJ MGP_FVBNJ_G0023484
protein coding gene Chr17:35017963-35040381 (+)
LP/J MGP_LPJ_G0023589
protein coding gene Chr17:37719831-37742717 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023507
protein coding gene Chr17:39095683-39119266 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024130
protein coding gene Chr17:36787996-36811110 (+)
PWK/PhJ MGP_PWKPhJ_G0022646
protein coding gene Chr17:34185663-34208130 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022465
protein coding gene Chr17:34868425-34893127 (+)
WSB/EiJ MGP_WSBEiJ_G0022961
protein coding gene Chr17:37101151-37125465 (+)



Homology
more
  • Human Ortholog
    TRIM26, tripartite motif containing 26
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TRIM26, tripartite motif containing 26
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AFP, RNF95, ZNF173
  • Links
    NCBI Gene ID: 7726
    neXtProt AC: NX_Q12899
    UniProt: Q12899

  • Chr Location
    6p22.1; chr6:30184453-30213494 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024457 Ensembl Gene Model | MGI Sequence Detail 22265 C57BL/6J ±  kb
transcript ENSMUST00000130367 Ensembl | MGI Sequence Detail 3187 Not Applicable  
polypeptide ENSMUSP00000114896 Ensembl | MGI Sequence Detail 545 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 72
    Genomic 8
    cDNA 63
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146873
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:47563 Yoshino M, et al., BAC/YAC contigs from the H2-M region of mouse chr 17 define gene order as Znf173-Tctex5-mog-D17Tu42-M3-M2. Immunogenetics. 1998 Apr;47(5):371-80
  • Latest
    J:245855 Wang P, et al., TRIM26 negatively regulates interferon-beta production and antiviral response through polyubiquitination and degradation of nuclear IRF3. PLoS Pathog. 2015 Mar;11(3):e1004726

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory