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Sdcbp
Gene Detail
Symbol

Name
ID
Sdcbp
syndecan binding protein
MGI:1337026
Synonyms
MDA-9, Sycl, syndecan interacting protein, syntenin, syntenin-1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
2.91 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:6365650-6408423 bp, + strand
From VEGA annotation of GRCm38

  42774 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4110  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SDCBP
Gene Tree: Sdcbp

Human
homologs
SDCBP, syndecan binding protein (syntenin)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6386
neXtProt AC: NX_O00560

Human Synonyms: MDA9, MDA-9, ST1, SYCL, TACIP18

Human Chr (Location): 8q12; chr8:58553169-58582860 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sdcbp interacts with 274 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process actin cytoskeleton organization, intracellular signal transduction, ...
Component blood microparticle, cytoplasm, ...
Function cell adhesion molecule binding, ephrin receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (55)    Tissues (44)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 55
cDNA source data(43)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sdcbp ; ZFIN sdcbp    NEW 
Molecular
reagents
All nucleic(44) cDNA(44)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000004316 (Evidence)
Ensembl Gene Model ENSMUSG00000028249 (Evidence)
Entrez Gene 53378 (Evidence)
DFCI TC1573740, TC1621300, TC1747513
NIA Mouse Gene Index U004047, U128085
Consensus CDS Project CCDS17951.1, CCDS51110.1
International Mouse Phenotyping Consortium Status Sdcbp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004316 VEGA Gene Model | MGI Sequence Detail 42774 C57BL/6J ±  kb
transcript OTTMUST00000009778 VEGA | MGI Sequence Detail 2745 Not Applicable 
polypeptide OTTMUSP00000004701 VEGA | MGI Sequence Detail 299 Not Applicable 

For the selected sequences
All sequences(133) RefSeq(6) UniProt(17)
Polymorphisms
SNPs within 2kb(225 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001478 PDZ domain
Protein Ontology PR:000014554 syntenin-1
References
(Earliest) J:113829 Grootjans JJ, et al., Syntenin, a PDZ protein that binds syndecan cytoplasmic domains. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13683-8
(Latest) J:195897 Jeon HY, et al., Expression patterns of MDA-9/syntenin during development of the mouse embryo. J Mol Histol. 2013 Apr;44(2):159-66
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory