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Sdcbp Gene Detail
Summary
  • Symbol
    Sdcbp
  • Name
    syndecan binding protein
  • Synonyms
    MDA-9, Sycl, syndecan interacting protein, syntenin, syntenin-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1337026
    NCBI Gene: 53378
Location & Maps
more
Homology
more
  • Human Ortholog
    SDCBP, syndecan binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SDCBP, syndecan binding protein
    Orthology source: HomoloGene
  • Synonyms
    MDA9, MDA-9, ST1, SYCL, TACIP18
  • Links
    NCBI Gene ID: 6386
    neXtProt AC: NX_O00560

  • Chr Location
    8q12; chr8:58553169-58582860 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4110
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SDCBP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    4
  • Targeted
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004316 VEGA Gene Model | MGI Sequence Detail 42774 C57BL/6J ±  kb
transcript OTTMUST00000009778 VEGA | MGI Sequence Detail 2745 Not Applicable  
polypeptide OTTMUSP00000004701 VEGA | MGI Sequence Detail 299 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    225 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44

    Microarray probesets 5
References
more
  • Summaries
    All 45
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:113829 Grootjans JJ, et al., Syntenin, a PDZ protein that binds syndecan cytoplasmic domains. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13683-8
  • Latest
    J:195897 Jeon HY, et al., Expression patterns of MDA-9/syntenin during development of the mouse embryo. J Mol Histol. 2013 Apr;44(2):159-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory