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Mocs2
Gene Detail
Symbol

Name
ID
Mocs2
molybdenum cofactor synthesis 2
MGI:1336894
Feature Type
protein coding gene
Genetic Map
Chromosome 13
64.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:114818236-114832275 bp, + strand
From VEGA annotation of GRCm38

  14040 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32193  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MOCS2
Protein SuperFamily: molybdopterin biosynthesis sulfur carrier protein
Gene Tree: Mocs2

Human
homologs
MOCS2, molybdenum cofactor synthesis 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4338
neXtProt AC: NX_O96007, NX_O96033

Human Synonyms: MCBPE, MOCO1, MOCODB, MPTS

Human Chr (Location): 5q11; chr5:53095679-53109772 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human MOCS2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Interactions
Mocs2 interacts with 127 markers (Mir1b, Mir7-1, Mir10a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
cDNA source data(85)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mocs2    NEW 
Molecular
reagents
All nucleic(85) cDNA(85)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000036446 (Evidence)
Ensembl Gene Model ENSMUSG00000015536 (Evidence)
Entrez Gene 17434 (Evidence)
UniGene 19027
DFCI TC1586812, TC1577259, TC1657110, TC1729537, TC1750272
DoTS DT.40136481, DT.110969618, DT.534467, DT.97402018, DT.94186953
NIA Mouse Gene Index U292935, U015268
EC 2.8.1.12
Consensus CDS Project CCDS49369.1, CCDS49370.1, CCDS49371.1
International Mouse Phenotyping Consortium Status Mocs2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036446 VEGA Gene Model | MGI Sequence Detail 14040 C57BL/6J ±  kb
transcript OTTMUST00000093386 VEGA | MGI Sequence Detail 1855 Not Applicable 
polypeptide OTTMUSP00000051784 VEGA | MGI Sequence Detail 189 Not Applicable 

For the selected sequences
All sequences(98) RefSeq(6) UniProt(6)
Polymorphisms
SNPs within 2kb(231 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012675 Beta-grasp domain
InterPro IPR003448 Molybdopterin biosynthesis MoaE
InterPro IPR010034 Molybdopterin converting factor, subunit 1
InterPro IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp
InterPro IPR003749 ThiamineS/Molybdopterin converting factor subunit 1
References
(Earliest) J:53881 Stallmeyer B, et al., Human molybdopterin synthase gene: identification of a bicistronic transcript with overlapping reading frames. Am J Hum Genet. 1999 Mar;64(3):698-705
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGI:2145228

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory