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Mocs2
Gene Detail
Symbol

Name
ID
Mocs2
molybdenum cofactor synthesis 2
MGI:1336894
Feature Type
protein coding gene
Genetic Map
Chromosome 13
64.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:114818236-114832275 bp, + strand
From VEGA annotation of GRCm38

  14040 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32193  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: molybdopterin biosynthesis sulfur carrier protein
Gene Tree: Mocs2

Human
homologs
Human Homolog MOCS2, molybdenum cofactor synthesis 2
NCBI Gene ID 4338
neXtProt AC  NX_O96007, NX_O96033
Human Synonyms  MCBPE, MOCO1, MOCODB, MPTS
Human Chr (Location)  5q11; chr5:53095679-53109772 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human MOCS2
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Interactions
Mocs2 interacts with 128 markers (Mir1b, Mir7-1, Mir10a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
cDNA source data(85)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(85) cDNA(85)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000036446 (Evidence)
Ensembl Gene ModelENSMUSG00000015536 (Evidence)
Entrez Gene17434 (Evidence)
UniGene19027
DFCITC1750272, TC1729537, TC1586812, TC1657110, TC1577259
DoTSDT.40136481, DT.534467, DT.110969618, DT.94186953, DT.97402018
NIA Mouse Gene IndexU015268, U292935
EC2.8.1.12
Consensus CDS ProjectCCDS49369.1, CCDS49370.1, CCDS49371.1
International Mouse Knockout Project StatusMocs2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036446 VEGA Gene Model | MGI Sequence Detail 14040 C57BL/6J ±  kb
transcript OTTMUST00000093386 VEGA | MGI Sequence Detail 1855 Not Applicable 
polypeptide OTTMUSP00000051784 VEGA | MGI Sequence Detail 189 Not Applicable 

For the selected sequences
All sequences(101) RefSeq(6) UniProt(10)
Polymorphisms
SNPs within 2kb(231 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012675 Beta-grasp domain
InterPro IPR003448 Molybdopterin biosynthesis MoaE
InterPro IPR010034 Molybdopterin converting factor, subunit 1
InterPro IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp
InterPro IPR003749 ThiamineS/Molybdopterin converting factor subunit 1
References
(Earliest) J:53881 Stallmeyer B, et al., Human molybdopterin synthase gene: identification of a bicistronic transcript with overlapping reading frames. Am J Hum Genet. 1999 Mar;64(3):698-705
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGI:2145228

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/23/2014
MGI 5.20
The Jackson Laboratory