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Slc6a20b Gene Detail
Summary
  • Symbol
    Slc6a20b
  • Name
    solute carrier family 6 (neurotransmitter transporter), member 20B
  • Synonyms
    Sit1, Slc6a20, XT3, Xtrp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336891
    NCBI Gene: 22599
  • Gene Overview
    MyGene.info: SLC6A20
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:123593823-123632538 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 74.19 cM, cytoband F4
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    279 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336891
 protein coding gene Chr9:123590800-123632565 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035479
 protein coding gene Chr9:126647246-126689174 (-)
A/J MGP_AJ_G0035460
 protein coding gene Chr9:121801028-121839023 (-)
AKR/J MGP_AKRJ_G0035393
 protein coding gene Chr9:125061567-125100680 (-)
BALB/cJ MGP_BALBcJ_G0035456
 protein coding gene Chr9:121735797-121768032 (-)
C3H/HeJ MGP_C3HHeJ_G0035163
 protein coding gene Chr9:125508030-125549358 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035979
 protein coding gene Chr9:130146590-130184798 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032861
 protein coding gene Chr9:118922555-118955718 (-)
CAST/EiJ MGP_CASTEiJ_G0034468
 protein coding gene Chr9:125551023-125613463 (-)
CBA/J MGP_CBAJ_G0035131
 protein coding gene Chr9:134900572-134925113 (-)
DBA/2J MGP_DBA2J_G0035290
 protein coding gene Chr9:121246270-121286397 (-)
FVB/NJ MGP_FVBNJ_G0035237
 protein coding gene Chr9:120150218-120185392 (-)
LP/J MGP_LPJ_G0035369
 protein coding gene Chr9:126981291-127003705 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035278
 protein coding gene Chr9:135687765-135736465 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035998
 protein coding gene Chr9:125527645-125561504 (-)
PWK/PhJ MGP_PWKPhJ_G0034172
 protein coding gene Chr9:121698920-121736258 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034009
 protein coding gene Chr9:125645087-125682104 (-)
WSB/EiJ MGP_WSBEiJ_G0034588
 protein coding gene Chr9:125369885-125407836 (-)



Homology
more
  • Human Ortholog
    SLC6A20, solute carrier family 6 member 20
  • Vertebrate Orthologs
    2
  • Human Ortholog
    SLC6A20, solute carrier family 6 member 20
    Orthology source: HGNC
  • Synonyms
    IMINO, SIT1, XT3, Xtrp3
  • Links
    NCBI Gene ID: 54716
    neXtProt AC: NX_Q9NP91
    UniProt: Q9NP91

  • Chr Location
    3p21.31; chr3:45755449-45796553 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    912
  • Tissues
    182
  • cDNA Data
    41
  • Literature Summary
    5
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22599 NCBI Gene Model | MGI Sequence Detail 38716 C57BL/6J ±  kb
transcript NM_011731 RefSeq | MGI Sequence Detail 3257 C57BL/6  
polypeptide O88575 UniProt | EBI | MGI Sequence Detail 635 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000015964 sodium- and chloride-dependent transporter XTRP3B
    (term hierarchy)
  • InterPro Domains
    IPR002438 Neutral amino acid SLC6 transporter
    IPR000175 Sodium:neurotransmitter symporter
    IPR037272 Sodium:neurotransmitter symporter superfamily
Molecular
Reagents
less
  • All nucleic 44
    cDNA 43
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142970
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:53016 Nash SR, et al., Cloning, gene structure and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms. Receptors Channels. 1998;6(2):113-28
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/12/2021
MGI 6.16 		The Jackson Laboratory