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Prdx6b Gene Detail
Summary
  • Symbol
    Prdx6b
  • Name
    peroxiredoxin 6B
  • Synonyms
    1-cysPrx-P1, 4930414C22Rik, Aop2-rs1, Prdx6-ps1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336888
    NCBI Gene: 320769
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:80292472-80295356 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 48.03 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336888
protein coding gene Chr2:80292470-80295358 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025882
protein coding gene Chr2:80863716-80866600 (+)
A/J MGP_AJ_G0025859
protein coding gene Chr2:77745869-77748753 (+)
AKR/J MGP_AKRJ_G0025828
protein coding gene Chr2:79781585-79784469 (+)
BALB/cJ MGP_BALBcJ_G0025855
protein coding gene Chr2:77879936-77882820 (+)
C3H/HeJ MGP_C3HHeJ_G0025614
protein coding gene Chr2:80017465-80020349 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026301
protein coding gene Chr2:83247079-83249963 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023704
protein coding gene Chr2:74969633-74972685 (+)
CAST/EiJ MGP_CASTEiJ_G0025076
protein coding gene Chr2:80445515-80448399 (+)
CBA/J MGP_CBAJ_G0025595
protein coding gene Chr2:86238903-86241793 (+)
DBA/2J MGP_DBA2J_G0025726
protein coding gene Chr2:77298072-77300956 (+)
FVB/NJ MGP_FVBNJ_G0025688
protein coding gene Chr2:76645968-76648852 (+)
LP/J MGP_LPJ_G0025814
protein coding gene Chr2:80728744-80731628 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025719
protein coding gene Chr2:88117800-88120683 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026357
protein coding gene Chr2:79947996-79950880 (+)
PWK/PhJ MGP_PWKPhJ_G0024819
protein coding gene Chr2:77238784-77241666 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024625
protein coding gene Chr2:80194407-80197295 (+)
WSB/EiJ MGP_WSBEiJ_G0025145
protein coding gene Chr2:80569912-80572795 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050114 Ensembl Gene Model | MGI Sequence Detail 2885 C57BL/6J ±  kb
transcript ENSMUST00000057072 Ensembl | MGI Sequence Detail 2885 Not Applicable  
polypeptide ENSMUSP00000133276 Ensembl | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
    IPR024706 Peroxiredoxin, AhpC-type
    IPR019479 Peroxiredoxin, C-terminal
    IPR013766 Thioredoxin domain
    IPR036249 Thioredoxin-like superfamily
Molecular
Reagents
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  • All nucleic 28
    Genomic 1
    cDNA 24
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
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MGI:1859817, MGI:2444701
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:51032 Phelan SA, et al., Characterization of the murine gene encoding Aop2 (antioxidant protein 2) and identification of two highly related genes. Genomics. 1998 Nov 15;54(1):132-9
  • Latest
    J:269738 Guerreiro I, et al., Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016 Aug 1;5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory