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Angpt4
Gene Detail
 Symbol
Name
ID
Angpt4
angiopoietin 4
MGI:1336887
Feature Type protein coding gene
Genetic Map
Chromosome 2
74.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:151911210-151945337 bp, + strand
From VEGA annotation of GRCm38

  34128 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36302  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Angpt4

Human
homologs
Human Homolog ANGPT4, angiopoietin 4
NCBI Gene ID 51378
neXtProt AC  NX_Q9Y264
Human Synonyms  AGP4, ANG-3, ANG4
Human Chr (Location)  20p13; chr20:872120-916334 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Angpt4 interacts with 96 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process activation of transmembrane receptor protein tyrosine kinase activity, angiogenesis, ...
Component extracellular region, extracellular space
Function receptor tyrosine kinase binding, transmembrane receptor protein tyrosine kinase activator activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000015844 (Evidence)
Ensembl Gene ModelENSMUSG00000027460 (Evidence)
Entrez Gene11602 (Evidence)
UniGene189536
DFCITC1614669
DoTSDT.99848076, DT.99854514
NIA Mouse Gene IndexU002631
Consensus CDS ProjectCCDS16874.1
International Mouse Knockout Project StatusAngpt4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015844 VEGA Gene Model | MGI Sequence Detail 34128 C57BL/6J ±  kb
transcript OTTMUST00000037663 VEGA | MGI Sequence Detail 2335 Not Applicable 
polypeptide OTTMUSP00000016888 VEGA | MGI Sequence Detail 509 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(284 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
InterPro IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
InterPro IPR014715 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
InterPro IPR020837 Fibrinogen, conserved site
Protein Ontology PR:000004025 angiopoietin-4
References (Earliest) J:53333 Valenzuela DM, et al., Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1904-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory