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Slc22a18
Gene Detail
Symbol

Name
ID
Slc22a18
solute carrier family 22 (organic cation transporter), member 18
MGI:1336884
Synonyms
BWR1A, BWSCR1A, Impt1, IMPT1, Orctl2, p45-BWR1A, Slc22a1l, TSSC5
Feature Type
protein coding gene
Genetic Map
Chromosome 7
88.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(15)
Sequence Map
Chr7:143473721-143499334 bp, + strand
From VEGA annotation of GRCm38

  25614 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1918  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: tetracycline resistance protein
Gene Tree: Slc22a18

Human
homologs
Human Homolog SLC22A18, solute carrier family 22, member 18
NCBI Gene ID 5002
neXtProt AC  NX_Q96BI1
Human Synonyms  BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, p45-BWR1A, SLC22A1L, TSSC5
Human Chr (Location)  11p15.5; chr11:2899721-2925246 (+)  GRCh38
Disease Associations  (3) Diseases Associated with Human SLC22A18
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc22a18 interacts with 132 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (15 records)
Data Summary: Results (280)    Tissues (165)    Images (35)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 245
Northern blot 24
RT-PCR 11
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(35) Genomic(14) cDNA(13) Primer pair(8)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000025376 (Evidence)
Ensembl Gene ModelENSMUSG00000000154 (Evidence)
Entrez Gene18400 (Evidence)
DFCITC1579021, TC1624255, TC1674215, TC1683075, TC1712543
DoTSDT.101329246, DT.101361438, DT.55148636, DT.94397401, DT.97414161
NIA Mouse Gene IndexU008992
Consensus CDS ProjectCCDS22041.1
International Mouse Knockout Project StatusSlc22a18
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025376 VEGA Gene Model | MGI Sequence Detail 25614 C57BL/6J ±  kb
transcript OTTMUST00000062468 VEGA | MGI Sequence Detail 1525 Not Applicable 
polypeptide OTTMUSP00000030799 VEGA | MGI Sequence Detail 410 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(16) UniProt(5)
Polymorphisms
PCR(5) : SNPs within 2kb(318 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
InterPro IPR001958 Tetracycline resistance protein, TetA/multidrug resistance protein MdtG
Protein Ontology PR:000014986 solute carrier family 22 member 18
References
(Earliest) J:10529 Bastian H, et al., A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner [published erratum appears in EMBO J 1991 Dec;10(12):3978]. EMBO J. 1990 Jun;9(6):1839-52
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(57)
Other
accession IDs
MGI:1202892, MGI:1332650, MGI:2142225

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory