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Mok Gene Detail
Summary
  • Symbol
    Mok
  • Name
    MOK protein kinase
  • Synonyms
    MAPK/MAK/MRK/ overlapping kinase, MOK, Rage, Stk30
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336881
    NCBI Gene: 26448
  • Gene Overview
    MyGene.info: MOK
Location & Maps
more
  • Sequence Map
    Chr12:110807798-110840939 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33142 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 60.81 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MOK, MOK protein kinase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MOK, MOK protein kinase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RAGE, RAGE1, RAGE-1, STK30
  • Links
    NCBI Gene ID: 5891
    neXtProt AC: NX_Q9UQ07

  • Chr Location
    14q32; chr14:102224450-102305200 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042052 VEGA Gene Model | MGI Sequence Detail 33142 C57BL/6J ±  kb
transcript OTTMUST00000110268 VEGA | MGI Sequence Detail 1693 Not Applicable  
polypeptide OTTMUSP00000061484 VEGA | MGI Sequence Detail 420 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    247 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 3
Other
Accession IDs
less
MGI:1347040
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:51213 Gopalan G, et al., A novel mammalian kinase, T/STK 30, is highly expressed in the germ line. Mol Reprod Dev. 1999 JAN;52(1):9-17
  • Latest
    J:202949 Chang DR, et al., Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory