Stk30
Gene Detail

Symbol Name ID

Stk30 serine/threonine kinase 30 MGI:1336881

Synonyms

MAPK/MAK/MRK/ overlapping kinase, MOK, Rage

Feature Type

protein coding gene

Genetic Map

Chromosome 12

60.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr12:110807798-110840939 bp, - strand From VEGA annotation of GRCm38   33142 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8062  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Stk30

Human homologs

Human Homolog		MOK, MOK protein kinase
NCBI Gene ID		5891
neXtProt AC		NX_Q9UQ07
Human Synonyms		RAGE, RAGE1, RAGE-1
Human Chr (Location)		14q32; chr14:102695178-102771531 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(239) : Targeted(2) Gene trapped(237)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	phosphorylation, protein phosphorylation
Component	cytoplasm
Function	ATP binding, cyclin-dependent protein serine/threonine kinase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (32)    Tissues (19)    Images (8)
Theiler Stages: 13, 19, 20, 21, 22, 23, 28

Assay Type	Results
RNA in situ	12
Northern blot	20

cDNA source data(25)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(25) cDNA(25)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000042052 (Evidence)
Ensembl Gene Model	ENSMUSG00000056458 (Evidence)
Entrez Gene	26448 (Evidence)
UniGene	140948
DFCI	TC1586571, TC1590757, TC1594617, TC1639487
NIA Mouse Gene Index	U034362
EC	2.7.11.22
Consensus CDS Project	CCDS49176.1
International Mouse Knockout Project Status	Stk30

Sequences

Length	Strain/Species
genomic	OTTMUSG00000042052	VEGA Gene Model | MGI Sequence Detail	33142	C57BL/6J
transcript	OTTMUST00000110268	VEGA | MGI Sequence Detail	1693	Not Applicable
polypeptide	OTTMUSP00000061484	VEGA | MGI Sequence Detail	420	Not Applicable

All sequences(32) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(200 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017441	Protein kinase, ATP binding site
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
InterPro	IPR002290	Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro	IPR008271	Serine/threonine-protein kinase, active site
Protein Ontology	PR:000013691	MAPK/MAK/MRK overlapping kinase

References

(Earliest) J:51213 Gopalan G, et al., A novel mammalian kinase, T/STK 30, is highly expressed in the germ line. Mol Reprod Dev. 1999 JAN;52(1):9-17
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)

Other accession IDs

MGI:1347040