About   Help   FAQ
Fkbp7 Gene Detail
Summary
  • Symbol
    Fkbp7
  • Name
    FK506 binding protein 7
  • Synonyms
    FKBP23
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336879
    NCBI Gene: 14231
Location & Maps
more
  • Sequence Map
    Chr2:76663044-76673116 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10073 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 45.09 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    FKBP7, FK506 binding protein 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FKBP7, FK506 binding protein 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FKBP23, PPIase
  • Links
    NCBI Gene ID: 51661
    neXtProt AC: NX_Q9Y680

  • Chr Location
    2q31.2; chr2:178463664-178480393 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 22568
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: FKBP7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    3 involving Fkbp7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013130 VEGA Gene Model | MGI Sequence Detail 10073 C57BL/6J ±  kb
transcript OTTMUST00000031693 VEGA | MGI Sequence Detail 860 Not Applicable  
polypeptide OTTMUSP00000014123 VEGA | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    115 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007543 peptidyl-prolyl cis-trans isomerase FKBP7
  • EC
  • InterPro Domains
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
    IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain
    IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
Molecular
Reagents
less
  • All nucleic 29
    cDNA 27
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:51036 Nakamura T, et al., Molecular cloning, characterization, and chromosomal localization of FKBP23, a novel FK506-binding protein with Ca2+-binding ability. Genomics. 1998 Nov 15;54(1):89-98
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/15/2016
MGI 6.04
The Jackson Laboratory