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Khsrp
Gene Detail
 Symbol
Name
ID
Khsrp
KH-type splicing regulatory protein
MGI:1336214
Synonyms 6330409F21Rik, KSRP
Feature Type protein coding gene
Genetic Map
Chromosome 17
29.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:57021058-57031507 bp, - strand
From Ensembl annotation of GRCm38

  10450 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2734  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 western clawed frog; 1 zebrafish

Gene Tree: Khsrp

Human
homologs
Human Homolog KHSRP, KH-type splicing regulatory protein
NCBI Gene ID 8570
neXtProt AC  NX_Q92945
Human Synonyms  FBP2, FUBP2, KSRP
Human Chr (Location)  19p13.3; chr19:6413104-6424811 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(12) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased susceptibility to HSV-1 infection.
 
Interactions
Khsrp interacts with 228 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process mRNA catabolic process, mRNA processing, ...
Component cytoplasm, cytoplasmic stress granule, ...
Function DNA binding, mRNA 3'-UTR binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (38)    Tissues (38)    Images (2)
Theiler Stages: 11, 13, 15, 19, 22, 23
Assay TypeResults
RNA in situ 38
cDNA source data(61)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(65) Genomic(1) cDNA(61) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000007670 (Evidence)
Entrez Gene16549 (Evidence)
UniGene34296
DFCITC1587675, TC1597270, TC1613182, TC1712524
DoTSDT.101143326, DT.101239148, DT.101383915, DT.110552423, DT.110552460
NIA Mouse Gene IndexU037966
Consensus CDS ProjectCCDS50157.1
International Mouse Knockout Project StatusKhsrp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000007670 Ensembl Gene Model | MGI Sequence Detail 10450 C57BL/6J ±  kb
transcript ENSMUST00000007814 Ensembl | MGI Sequence Detail 3990 Not Applicable 
polypeptide ENSMUSP00000007814 Ensembl | MGI Sequence Detail 748 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(2)
Polymorphisms PCR(1) : SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015096 Domain of unknown function DUF1897
InterPro IPR004087 K Homology domain
InterPro IPR004088 K Homology domain, type 1
Protein Ontology PR:000009283 far upstream element-binding protein 2
References (Earliest) J:54030 Ring HZ, et al., Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17. Genomics. 1999 Mar 15;56(3):350-2
(Latest) J:203082 Briata P, et al., PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis. Cell Death Differ. 2012 Mar;19(3):478-87
All references(45)
Other
accession IDs
MGI:1917993

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory