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Mybpc1
Gene Detail
Symbol

Name
ID
Mybpc1
myosin binding protein C, slow-type
MGI:1336213
Synonyms
8030451F13Rik, Slow-type C-protein
Feature Type
protein coding gene
Genetic Map
Chromosome 10
43.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:88518279-88605152 bp, - strand
From VEGA annotation of GRCm38

  86874 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1846  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MYBPC1
Gene Tree: Mybpc1

Human
homologs
MYBPC1, myosin binding protein C, slow type
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4604
neXtProt AC: NX_Q00872

Human Synonyms: LCCS4, MYBPCC, MYBPCS

Human Chr (Location): 12q23.2; chr12:101594931-101685883 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human MYBPC1

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(12) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Mybpc1 interacts with 107 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process muscle contraction, positive regulation of protein targeting to mitochondrion
Component cytoskeleton
Function structural constituent of cytoskeleton
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (221)    Tissues (78)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 196
Northern blot 25
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mybpc1 ; ZFIN mybpc1    NEW 
Molecular
reagents
All nucleic(24) cDNA(24)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000031731 (Evidence)
Ensembl Gene Model ENSMUSG00000020061 (Evidence)
Entrez Gene 109272 (Evidence)
UniGene 147208
DFCI TC1708473, TC1583332, TC1653747, TC1595437
DoTS DT.87072334, DT.110618125, DT.87068479, DT.87055030
NIA Mouse Gene Index U032105
Consensus CDS Project CCDS48666.1, CCDS56739.1
International Mouse Phenotyping Consortium Status Mybpc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031731 VEGA Gene Model | MGI Sequence Detail 86874 C57BL/6J ±  kb
transcript OTTMUST00000078595 VEGA | MGI Sequence Detail 3752 Not Applicable 
polypeptide OTTMUSP00000041816 VEGA | MGI Sequence Detail 1127 Not Applicable 

For the selected sequences
All sequences(89) RefSeq(42) UniProt(6)
Polymorphisms
SNPs within 2kb(1123 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013098 Immunoglobulin I-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR003598 Immunoglobulin subtype 2
Protein Ontology PR:000010803 myosin-binding protein C, slow-type
References
(Earliest) J:32589 Schiaffino S, et al., Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol Rev. 1996 Apr;76(2):371-423
(Latest) J:213153 Harms MJ, et al., Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604
All references(35)
Other
accession IDs
MGI:1924741

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory