Mybpc1
Gene Detail

Symbol Name ID

Mybpc1 myosin binding protein C, slow-type MGI:1336213

Synonyms

8030451F13Rik, Slow-type C-protein

Feature Type

protein coding gene

Genetic Map

Chromosome 10

43.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr10:88518279-88605152 bp, - strand From VEGA annotation of GRCm38   86874 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1846  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mybpc1

Human homologs

Human Homolog		MYBPC1, myosin binding protein C, slow type
NCBI Gene ID		4604
neXtProt AC		NX_Q00872
Human Synonyms		LCCS4, MYBPCC, MYBPCS
Human Chr (Location)		12q23.2; chr12:101988709-102079658 (+)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human MYBPC1

Alleles and phenotypes

All alleles(14) : Targeted(2) Gene trapped(12)

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process	muscle contraction
Component	cytoskeleton
Function	structural constituent of cytoskeleton

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (215)    Tissues (72)    Images (24)
Theiler Stages: 16, 18, 20, 21, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	190
Northern blot	25

cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(24)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000031731 (Evidence)
Ensembl Gene Model	ENSMUSG00000020061 (Evidence)
Entrez Gene	109272 (Evidence)
UniGene	147208
DFCI	TC1583332, TC1595437, TC1653747, TC1708473
DoTS	DT.110618125, DT.87055030, DT.87068479, DT.87072334
NIA Mouse Gene Index	U032105
Consensus CDS Project	CCDS48666.1, CCDS56739.1
International Mouse Knockout Project Status	Mybpc1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031731	VEGA Gene Model | MGI Sequence Detail	86874	C57BL/6J
transcript	OTTMUST00000078595	VEGA | MGI Sequence Detail	3752	Not Applicable
polypeptide	OTTMUSP00000041816	VEGA | MGI Sequence Detail	1127	Not Applicable

All sequences(49) RefSeq(4) UniProt(5)

Polymorphisms

SNPs(673 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003961	Fibronectin, type III
InterPro	IPR013098	Immunoglobulin I-set
InterPro	IPR007110	Immunoglobulin-like domain
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR003598	Immunoglobulin subtype 2
Protein Ontology	PR:000010803	myosin-binding protein C, slow-type

References

(Earliest) J:32589 Schiaffino S, et al., Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol Rev. 1996 Apr;76(2):371-423
(Latest) J:193107 Jin C, et al., Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Dev Biol. 2013 Feb 1;374(1):96-107
All references(32)

Other accession IDs

MGI:1924741