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Mybpc1 Gene Detail
Summary
  • Symbol
    Mybpc1
  • Name
    myosin binding protein C, slow-type
  • Synonyms
    8030451F13Rik, Slow-type C-protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336213
    NCBI Gene: 109272
  • Gene Overview
    MyGene.info: MYBPC1
Location & Maps
more
  • Sequence Map
    Chr10:88518279-88605152 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      86874 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MYBPC1, myosin binding protein C, slow type
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYBPC1, myosin binding protein C, slow type
    Orthology source: HomoloGene
  • Synonyms
    LCCS4, MYBPCC, MYBPCS
  • Links
    NCBI Gene ID: 4604
    neXtProt AC: NX_Q00872

  • Chr Location
    12q23.2; chr12:101594931-101685883 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 1846
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MYBPC1
  • Gene Tree
Human Diseases
more
  • Diseases
    2 with human MYBPC1 associations

Human Disease Mouse Models
       Arthrogryposis, Distal, Type 1B; DA1B   OMIM: 614335
Lethal Congenital Contracture Syndrome 4; LCCS4   OMIM: 614915
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    1
  • Gene trapped
    12
  • Targeted
    2
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Mybpc1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031731 VEGA Gene Model | MGI Sequence Detail 86874 C57BL/6J ±  kb
transcript OTTMUST00000078595 VEGA | MGI Sequence Detail 3752 Not Applicable  
polypeptide OTTMUSP00000041816 VEGA | MGI Sequence Detail 1127 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1112 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 2
Other
Accession IDs
less
MGI:1924741
References
more
  • Summaries
    All 31
    Developmental Gene Expression 9
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:32589 Schiaffino S, et al., Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol Rev. 1996 Apr;76(2):371-423
  • Latest
    J:213153 Harms MJ, et al., Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory